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Catalog Number:
37726
CAS Number:
154-93-8
Carmustine
Purity:
≥ 98% (HPLC)
Synonym(s):
1,3-Bis(2-chloroethyl)-1-nitrosourea
Hazmat
Documents
$228.24 /100MG
Pack Size Availability Price
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Product Information

Carmustine is a potent alkylating agent widely recognized for its application in oncology, particularly in the treatment of brain tumors and multiple myeloma. As a member of the nitrosourea class, it functions by interfering with DNA replication, making it effective against rapidly dividing cancer cells. Its unique ability to cross the blood-brain barrier enhances its efficacy in treating central nervous system malignancies, providing a critical therapeutic option where other treatments may fall short.

In addition to its primary use in cancer therapy, Carmustine is also employed in research settings, particularly in studies focused on the mechanisms of cancer resistance and the development of novel chemotherapeutic agents. Its versatility and effectiveness make it a valuable compound for both clinical and laboratory applications, offering researchers and healthcare professionals a reliable tool in the fight against cancer. With its established track record, Carmustine continues to be a cornerstone in cancer treatment protocols, demonstrating significant potential for improving patient outcomes.

Synonyms
1,3-Bis(2-chloroethyl)-1-nitrosourea
CAS Number
154-93-8
Purity
≥ 98% (HPLC)
Molecular Formula
C5H9Cl2N3O2
Molecular Weight
214.05
MDL Number
MFCD00057706
PubChem ID
2578
Melting Point
32 ?C
Appearance
White to almost white powder to crystal
Conditions
Store at < -20 °C
General Information
Synonyms
1,3-Bis(2-chloroethyl)-1-nitrosourea
CAS Number
154-93-8
Purity
≥ 98% (HPLC)
Molecular Formula
C5H9Cl2N3O2
Molecular Weight
214.05
MDL Number
MFCD00057706
PubChem ID
2578
Melting Point
32 ?C
Appearance
White to almost white powder to crystal
Conditions
Store at < -20 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Carmustine is widely utilized in research focused on:

  • Cancer Treatment: Primarily used as a chemotherapy agent for treating various types of cancers, including brain tumors and multiple myeloma. Its ability to cross the blood-brain barrier makes it particularly effective for central nervous system cancers.
  • Veterinary Medicine: Employed in veterinary oncology for treating tumors in pets, providing an option for pet owners seeking advanced treatment for their animals.
  • Research Applications: Utilized in laboratory settings to study cancer cell behavior and resistance mechanisms, helping researchers develop new therapeutic strategies.
  • Drug Formulation: Incorporated in the development of combination therapies, enhancing the effectiveness of other anticancer drugs and reducing the likelihood of drug resistance.
  • Pharmaceutical Development: Serves as a model compound in the synthesis of new nitrosourea derivatives, aiding in the discovery of novel anticancer agents with improved efficacy and safety profiles.

Citations