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Catalog Number:
37708
CAS Number:
6055-19-2
Cyclophosphamide monohydrate
Synonym(s):
2-[Bis(2-chloroethyl)amino]tetrahydro-1,3,2-oxazaphosphorin-2-oxide monohydrate
Hazmat
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Product Information

Cyclophosphamide monohydrate is a potent alkylating agent widely recognized for its application in oncology and immunology. This compound is primarily utilized in the treatment of various cancers, including lymphomas and leukemias, due to its ability to interfere with DNA replication and cell division. Its effectiveness in chemotherapy regimens makes it a critical component in cancer treatment protocols. Additionally, cyclophosphamide monohydrate is employed in the management of autoimmune disorders, showcasing its versatility beyond oncology.

Researchers and industry professionals appreciate cyclophosphamide monohydrate for its unique properties, such as its solubility and stability, which enhance its bioavailability and therapeutic efficacy. The compound's ability to cross-link DNA strands provides a mechanism for inducing apoptosis in malignant cells, making it a valuable tool in both clinical and research settings. With its established role in cancer therapy and potential in treating autoimmune diseases, cyclophosphamide monohydrate continues to be a significant compound in pharmaceutical development and therapeutic applications.

Synonyms
2-[Bis(2-chloroethyl)amino]tetrahydro-1,3,2-oxazaphosphorin-2-oxide monohydrate
CAS Number
6055-19-2
Molecular Formula
C7H15Cl2N2O2P·H2O
Molecular Weight
279.1
MDL Number
MFCD00149395
PubChem ID
22420
Melting Point
49-53 ?C
Appearance
White crystalline powder
Conditions
Store at 2-8°C
General Information
Synonyms
2-[Bis(2-chloroethyl)amino]tetrahydro-1,3,2-oxazaphosphorin-2-oxide monohydrate
CAS Number
6055-19-2
Molecular Formula
C7H15Cl2N2O2P·H2O
Molecular Weight
279.1
MDL Number
MFCD00149395
PubChem ID
22420
Melting Point
49-53 ?C
Appearance
White crystalline powder
Conditions
Store at 2-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Cyclophosphamide monohydrate is widely utilized in research focused on:

  • Cancer Treatment: This compound is primarily used as a chemotherapy agent for various types of cancers, including lymphomas and leukemias, helping to inhibit cancer cell growth effectively.
  • Immunosuppression: It is employed in organ transplantation and autoimmune disease management to suppress the immune response, reducing the risk of rejection and managing conditions like lupus.
  • Pharmaceutical Research: Researchers use cyclophosphamide monohydrate to study drug interactions and mechanisms of action in cancer therapies, providing insights into more effective treatment protocols.
  • Veterinary Medicine: This compound is also applied in veterinary oncology, treating tumors in animals, thus improving their quality of life and treatment outcomes.
  • Formulation Development: In the pharmaceutical industry, it is used in the development of various drug formulations, benefiting from its solubility and stability characteristics compared to other chemotherapeutic agents.

Citations