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Catalog Number:
37702
CAS Number:
51481-61-9
Cimetidine
Purity:
≥ 99% (Assay by titration, HPLC)
Synonym(s):
2-Cyano-1-methyl-3-[2-(5-methyl-1H-imidazol-4-yl-methylthio)ethyl]guanidine
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Product Information

Cimetidine is a widely recognized histamine H2-receptor antagonist, primarily used in the treatment of conditions such as peptic ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome. This compound works by inhibiting stomach acid production, providing relief from symptoms associated with excessive gastric acid secretion. Its unique structure allows for effective binding to H2 receptors, making it a valuable option for both acute and chronic management of acid-related disorders.

In addition to its therapeutic applications, Cimetidine has been explored for its potential role in enhancing the bioavailability of certain drugs, making it a subject of interest in pharmaceutical research. Its ability to inhibit cytochrome P450 enzymes can influence the metabolism of co-administered medications, which is crucial for optimizing drug efficacy and safety. Researchers and healthcare professionals appreciate Cimetidine not only for its direct applications in treating gastrointestinal conditions but also for its broader implications in drug interaction studies and pharmacokinetics.

Synonyms
2-Cyano-1-methyl-3-[2-(5-methyl-1H-imidazol-4-yl-methylthio)ethyl]guanidine
CAS Number
51481-61-9
Purity
≥ 99% (Assay by titration, HPLC)
Molecular Formula
C10H16N6S
Molecular Weight
252.34
MDL Number
MFCD00133296
PubChem ID
2756
Melting Point
141 - 143 ?C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2-Cyano-1-methyl-3-[2-(5-methyl-1H-imidazol-4-yl-methylthio)ethyl]guanidine
CAS Number
51481-61-9
Purity
≥ 99% (Assay by titration, HPLC)
Molecular Formula
C10H16N6S
Molecular Weight
252.34
MDL Number
MFCD00133296
PubChem ID
2756
Melting Point
141 - 143 ?C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Cimetidine is widely utilized in research focused on

  • Gastrointestinal Health: Primarily used to treat conditions like peptic ulcers and gastroesophageal reflux disease (GERD), Cimetidine helps reduce stomach acid production, providing relief to patients.
  • Pharmacological Research: It serves as a valuable tool in studies investigating histamine receptors and their role in various physiological processes, aiding researchers in understanding drug interactions and mechanisms.
  • Drug Interaction Studies: Cimetidine is often employed in clinical trials to assess its effects on the metabolism of other medications, helping to identify potential drug interactions and optimize therapeutic regimens.
  • Veterinary Medicine: This compound is also used in veterinary practices to manage similar gastrointestinal issues in animals, showcasing its versatility across species.
  • Histamine-Related Disorders: Cimetidine's ability to block histamine receptors makes it useful in treating conditions related to excessive histamine release, such as certain allergies, enhancing patient care in allergy management.

Citations