Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
37657
CAS Number:
3543-75-7
Bendamustine hydrochloride hydrate
Purity:
≥ 98% (Assay, HPLC)
Synonym(s):
5-[Bis(2-chloroethyl)amino]-1-methylbenzimidazole-2-butyric acid hydrochloride hydrate
Hazmat
Documents
$260.69 /200MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Bendamustine hydrochloride hydrate is a potent chemotherapeutic agent primarily used in the treatment of various hematological malignancies, including chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma. This compound combines the properties of a traditional alkylating agent with those of a purine analog, making it effective in disrupting DNA synthesis and promoting apoptosis in cancer cells. Its unique mechanism of action allows for a more targeted approach, which can lead to improved efficacy and reduced toxicity compared to other chemotherapy agents.

In addition to its applications in oncology, Bendamustine hydrochloride hydrate is also being explored for use in combination therapies, enhancing the effectiveness of existing treatment regimens. Researchers appreciate its versatility in clinical settings, as it can be administered intravenously or orally, providing flexibility in patient care. With ongoing studies investigating its potential in treating other malignancies and its favorable safety profile, Bendamustine hydrochloride hydrate remains a valuable compound in the arsenal against cancer.

Synonyms
5-[Bis(2-chloroethyl)amino]-1-methylbenzimidazole-2-butyric acid hydrochloride hydrate
CAS Number
3543-75-7
Purity
≥ 98% (Assay, HPLC)
Molecular Formula
C16H21Cl2N3O2·HCl·xH2O
Molecular Weight
394.72
MDL Number
MFCD16879055
PubChem ID
77082
Melting Point
165 - 169 ?C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
5-[Bis(2-chloroethyl)amino]-1-methylbenzimidazole-2-butyric acid hydrochloride hydrate
CAS Number
3543-75-7
Purity
≥ 98% (Assay, HPLC)
Molecular Formula
C16H21Cl2N3O2·HCl·xH2O
Molecular Weight
394.72
MDL Number
MFCD16879055
PubChem ID
77082
Melting Point
165 - 169 ?C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Bendamustine hydrochloride hydrate is widely utilized in research focused on:

  • Cancer Treatment: Primarily used in oncology, it is effective for treating chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma, providing a targeted approach that minimizes damage to healthy cells.
  • Combination Therapies: Often combined with other chemotherapeutic agents, enhancing the overall efficacy of treatment regimens while potentially reducing side effects compared to traditional chemotherapy.
  • Research in Drug Development: Serves as a model compound in pharmacology studies, helping researchers understand drug interactions and resistance mechanisms in cancer cells.
  • Pharmaceutical Formulations: Used in the development of injectable formulations, allowing for precise dosing and improved patient compliance in clinical settings.
  • Clinical Trials: Frequently involved in clinical research to evaluate new treatment protocols, contributing to advancements in cancer therapy and improving patient outcomes.

Citations