Powered by Bioz
10-Hydroxycamptothecin
10-Hydroxycamptothecin is widely utilized in research focused on
- Cancer Treatment: This compound is a potent inhibitor of topoisomerase I, making it valuable in developing anticancer therapies. It has shown effectiveness against various cancers, including colorectal and ovarian cancers.
- Pharmaceutical Development: Researchers are exploring its derivatives to enhance solubility and bioavailability, leading to more effective drug formulations. This is crucial for improving patient outcomes in cancer therapy.
- Drug Combination Studies: 10-Hydroxycamptothecin is often used in combination with other chemotherapeutic agents to assess synergistic effects, helping to optimize treatment regimens for better efficacy.
- Research on Mechanisms of Action: It serves as a model compound in studies investigating the mechanisms of DNA damage and repair, contributing to a deeper understanding of cellular responses to chemotherapy.
- Natural Product Synthesis: This compound is derived from the Camptotheca acuminata tree, and its study promotes sustainable sourcing and synthesis of natural products, appealing to eco-conscious researchers and industries.
General Information
Properties
Safety and Regulations
Applications
10-Hydroxycamptothecin is widely utilized in research focused on
- Cancer Treatment: This compound is a potent inhibitor of topoisomerase I, making it valuable in developing anticancer therapies. It has shown effectiveness against various cancers, including colorectal and ovarian cancers.
- Pharmaceutical Development: Researchers are exploring its derivatives to enhance solubility and bioavailability, leading to more effective drug formulations. This is crucial for improving patient outcomes in cancer therapy.
- Drug Combination Studies: 10-Hydroxycamptothecin is often used in combination with other chemotherapeutic agents to assess synergistic effects, helping to optimize treatment regimens for better efficacy.
- Research on Mechanisms of Action: It serves as a model compound in studies investigating the mechanisms of DNA damage and repair, contributing to a deeper understanding of cellular responses to chemotherapy.
- Natural Product Synthesis: This compound is derived from the Camptotheca acuminata tree, and its study promotes sustainable sourcing and synthesis of natural products, appealing to eco-conscious researchers and industries.
Documents
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
Product Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
*Catalog Number
*Lot Number
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.
*Catalog Number
*Lot Number
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
DownloadProduct Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
DownloadCertificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
*Catalog Number
*Lot Number
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.