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Catalog Number:
22995
CAS Number:
298-81-7
8-Methoxypsoralen (Xanthotoxin)
Grade:
meets USP specifications
Purity:
98 - 102% (HPLC)
Synonym(s):
9-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one, Xanthotoxin
Documents
$22.03 /1G
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Product Information

8-Methoxypsoralen, also known as Xanthotoxin, is a naturally occurring compound that belongs to the class of furanocoumarins. This versatile chemical is primarily recognized for its applications in the field of dermatology, particularly in photochemotherapy for skin conditions such as psoriasis and vitiligo. By enhancing the skin's sensitivity to ultraviolet light, 8-Methoxypsoralen facilitates effective treatment protocols that promote skin repigmentation and alleviate symptoms.

In addition to its therapeutic uses, 8-Methoxypsoralen is also utilized in research settings, particularly in studies involving DNA intercalation and photobiology. Its unique ability to form covalent bonds with DNA upon UV irradiation makes it a valuable tool for investigating cellular processes and mechanisms of action in various biological systems. With its dual role in both clinical and research applications, 8-Methoxypsoralen stands out as a compound of significant interest for professionals in the pharmaceutical and biomedical fields.

Synonyms
9-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one, Xanthotoxin
CAS Number
298-81-7
Purity
98 - 102% (HPLC)
Grade
meets USP specifications
Molecular Formula
C12H8O4
Molecular Weight
216.2
MDL Number
MFCD00005009
PubChem ID
4114
Melting Point
143 - 148 ?C
Appearance
White crystalline powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
9-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one, Xanthotoxin
CAS Number
298-81-7
Purity
98 - 102% (HPLC)
Grade
meets USP specifications
Molecular Formula
C12H8O4
Molecular Weight
216.2
MDL Number
MFCD00005009
PubChem ID
4114
Melting Point
143 - 148 ?C
Appearance
White crystalline powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

8-Methoxypsoralen is widely utilized in research focused on:

  • Phototherapy for Skin Disorders: This compound is commonly used in the treatment of psoriasis and vitiligo, where it enhances the effectiveness of ultraviolet light therapy, leading to improved skin conditions.
  • Research in Cancer Treatment: It is being studied for its potential in cancer therapies, particularly in combination with other drugs to increase the efficacy of treatments by targeting cancer cells more effectively.
  • Antimicrobial Applications: 8-Methoxypsoralen exhibits antimicrobial properties, making it useful in developing treatments for infections, particularly those resistant to conventional antibiotics.
  • Pharmaceutical Development: The compound serves as a lead structure for synthesizing new drugs, providing a basis for creating novel therapeutic agents with improved efficacy and safety profiles.
  • Research in Genetic Studies: It is utilized in studies involving DNA intercalation, which helps researchers understand genetic mutations and the mechanisms of various diseases.

Citations