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Catalog Number:
22116
CAS Number:
15663-27-1
cis-Diammineplatinum(II)dichloride
Purity:
98 - 102% (HPLC) (64.42 - 65.22% Pt content)
Synonym(s):
cis-Dichlorodiammine platinum(II), cis-Platinum(II) diammine dichloride, Cisplatin
Hazmat
Documents
$108.36 /250MG
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Product Information

cis-Diammineplatinum(II)dichloride, commonly known as cisplatin, is a potent chemotherapeutic agent widely utilized in oncology for the treatment of various cancers, including testicular, ovarian, bladder, and lung cancers. This compound is characterized by its ability to form DNA cross-links, which inhibit DNA replication and transcription, ultimately leading to cancer cell death. Its unique mechanism of action distinguishes it from other anticancer drugs, making it a cornerstone in combination therapies. Researchers and healthcare professionals appreciate cisplatin for its effectiveness and the extensive clinical data supporting its use, which enhances treatment protocols and patient outcomes.

In addition to its primary role in cancer therapy, cis-Diammineplatinum(II)dichloride is also being explored for its potential applications in targeted drug delivery systems and as a model compound in biochemical research. Its solubility and stability in various environments make it a valuable tool for studying cellular responses to platinum-based therapies. With ongoing research into its mechanisms and potential new applications, cisplatin continues to hold promise for improving cancer treatment strategies and expanding therapeutic options.

Synonyms
cis-Dichlorodiammine platinum(II), cis-Platinum(II) diammine dichloride, Cisplatin
CAS Number
15663-27-1
Purity
98 - 102% (HPLC) (64.42 - 65.22% Pt content)
Molecular Formula
Pt(NH32Cl2
Molecular Weight
300.05
MDL Number
MFCD00011623
PubChem ID
84691
Appearance
Yellow crystalline powder
Conditions
Store at 0-8 °C
General Information
Synonyms
cis-Dichlorodiammine platinum(II), cis-Platinum(II) diammine dichloride, Cisplatin
CAS Number
15663-27-1
Purity
98 - 102% (HPLC) (64.42 - 65.22% Pt content)
Molecular Formula
Pt(NH32Cl2
Molecular Weight
300.05
MDL Number
MFCD00011623
PubChem ID
84691
Appearance
Yellow crystalline powder
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

cis-Diammineplatinum(II)dichloride is widely utilized in research focused on:

  • Cancer Treatment: This compound is a key ingredient in chemotherapy drugs, particularly for treating various types of cancer, including testicular and ovarian cancers, by interfering with DNA replication in cancer cells.
  • Pharmaceutical Development: It serves as a model compound in drug formulation studies, helping researchers understand the mechanisms of drug action and resistance in cancer therapies.
  • Analytical Chemistry: Used in analytical methods to detect and quantify platinum in biological samples, aiding in the monitoring of drug levels in patients undergoing treatment.
  • Material Science: Employed in the development of novel materials, such as sensors and catalysts, due to its unique chemical properties and ability to form stable complexes.
  • Biochemical Research: Acts as a tool in studies investigating cellular processes, including apoptosis and cell signaling pathways, providing insights into the effects of platinum-based drugs on cellular functions.

Citations