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Catalog Number:
01958
CAS Number:
3902-71-4
Trioxsalen
Grade:
meets USP specifications
Purity:
97-103% (HPLC)
Synonym(s):
4,5',8-Trimethylpsoralen, 2,5,9-Trimethyl-furo[3,2-g]benzopyran-7-one
Hazmat
Documents
$51.18 /1G
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Product Information

Trioxsalen is a potent compound recognized for its applications in the field of dermatology and phototherapy. This furocoumarin derivative is primarily utilized in the treatment of skin disorders, particularly psoriasis and vitiligo, due to its ability to enhance the skin's sensitivity to ultraviolet light. By promoting the production of melanin and facilitating skin repigmentation, Trioxsalen serves as an effective therapeutic agent in combination with UV light exposure. Its unique structure allows for selective binding to DNA, which not only aids in the treatment of skin conditions but also opens avenues for research in photobiology and photochemistry.

In addition to its therapeutic uses, Trioxsalen is valuable in various research applications, including studies on DNA damage and repair mechanisms. Its ability to intercalate into DNA makes it a useful tool for scientists investigating the effects of UV radiation on genetic material. With its dual role in both clinical and research settings, Trioxsalen stands out as a versatile compound that offers significant benefits to healthcare professionals and researchers alike.

Synonyms
4,5',8-Trimethylpsoralen, 2,5,9-Trimethyl-furo[3,2-g]benzopyran-7-one
CAS Number
3902-71-4
Purity
97-103% (HPLC)
Grade
meets USP specifications
Molecular Formula
C14H12O3
Molecular Weight
228.25
MDL Number
MFCD00005010
PubChem ID
5585
Melting Point
228-232 ?C
Appearance
White to off white or grayish crystalline
Conditions
Store at 0-8 °C
General Information
Synonyms
4,5',8-Trimethylpsoralen, 2,5,9-Trimethyl-furo[3,2-g]benzopyran-7-one
CAS Number
3902-71-4
Purity
97-103% (HPLC)
Grade
meets USP specifications
Molecular Formula
C14H12O3
Molecular Weight
228.25
MDL Number
MFCD00005010
PubChem ID
5585
Melting Point
228-232 ?C
Appearance
White to off white or grayish crystalline
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Trioxsalen is widely utilized in research focused on:

  • Phototherapy for Skin Disorders: This compound is effective in treating psoriasis and vitiligo by enhancing skin pigmentation when exposed to ultraviolet light.
  • DNA Research: Trioxsalen is used as a cross-linking agent in molecular biology, allowing researchers to study DNA interactions and repair mechanisms.
  • Pharmaceutical Development: It plays a role in the formulation of drugs that require photochemical activation, providing a targeted approach to drug delivery.
  • Cosmetic Applications: The compound is incorporated into products aimed at skin rejuvenation, leveraging its ability to promote cellular turnover and repair.
  • Research in Cancer Treatment: Trioxsalen is being explored for its potential in photodynamic therapy, targeting cancer cells with light-activated compounds.

Citations