Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
02038
CAS Number:
389-08-2
Nalidixic acid
Purity:
≥ 99% (On dry basis)
Synonym(s):
1,4-Dihydro-1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylicacid
Documents
$18.50 /5G
Pack Size Availability Price
Request Bulk Quote
Product Information

Nalidixic acid is a synthetic antibacterial agent belonging to the quinolone class, primarily recognized for its effectiveness against a variety of gram-negative bacterial infections. This compound is particularly valuable in the treatment of urinary tract infections and has been utilized in clinical settings since its introduction. Its mechanism of action involves inhibiting bacterial DNA gyrase, which is crucial for DNA replication, thereby preventing the growth and reproduction of bacteria. Researchers and healthcare professionals appreciate Nalidixic acid for its targeted action and relatively low toxicity, making it a preferred choice in specific therapeutic applications.

In addition to its medicinal uses, Nalidixic acid serves as a vital tool in microbiological research, where it is employed to study bacterial resistance mechanisms and the efficacy of new antimicrobial agents. Its unique structure allows for modifications that can enhance its antibacterial properties, paving the way for the development of novel derivatives with improved activity. This versatility makes Nalidixic acid an essential compound for both clinical and research applications, providing significant benefits in the fight against bacterial infections.

Synonyms
1,4-Dihydro-1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylicacid
CAS Number
389-08-2
Purity
≥ 99% (On dry basis)
Molecular Formula
C12H12N2O3
Molecular Weight
232.2
MDL Number
MFCD00006884
PubChem ID
4421
Melting Point
227-229°C
Appearance
Almost white to slight yellow crystalline powder
Conditions
Store at RT
General Information
Synonyms
1,4-Dihydro-1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylicacid
CAS Number
389-08-2
Purity
≥ 99% (On dry basis)
Molecular Formula
C12H12N2O3
Molecular Weight
232.2
MDL Number
MFCD00006884
PubChem ID
4421
Melting Point
227-229°C
Appearance
Almost white to slight yellow crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Nalidixic acid is widely utilized in research focused on

  • Antibacterial Treatments: This compound is primarily used in the development of antibacterial medications, particularly for treating urinary tract infections caused by susceptible bacteria.
  • Pharmaceutical Research: Researchers explore nalidixic acid's properties to develop new antibiotics, enhancing efficacy and reducing resistance compared to older treatments.
  • Analytical Chemistry: It serves as a standard in analytical methods for detecting and quantifying quinolone antibiotics in various samples, ensuring quality control in pharmaceutical manufacturing.
  • Veterinary Medicine: Nalidixic acid is also applied in veterinary practices to treat bacterial infections in animals, providing a reliable option for animal health professionals.
  • Microbial Resistance Studies: The compound is used in studies investigating bacterial resistance mechanisms, helping to inform the development of more effective antibiotics.

Citations