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Catalog Number:
01961
CAS Number:
530-43-8
Chloramphenicol palmitate
Grade:
meets BP specifications
Purity:
98 - 102% (Assay by titration, on dry basis)
Synonym(s):
Chloramphenicol α-palmitate
Antibiotic
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Product Information

Chloramphenicol palmitate is a palmitate ester of chloramphenicol, a broad-spectrum antibiotic known for its effectiveness against a variety of bacterial infections. This compound is particularly valued in pharmaceutical formulations, especially in pediatric medicine, due to its improved solubility and palatability compared to its parent compound. Chloramphenicol palmitate is often utilized in oral suspensions, making it easier for children to ingest while ensuring effective treatment of infections such as typhoid fever and bacterial meningitis.

In addition to its medicinal applications, Chloramphenicol palmitate serves as a critical intermediate in the synthesis of other pharmaceutical compounds, showcasing its versatility in drug development. Its unique properties, such as enhanced stability and bioavailability, make it a preferred choice for researchers and industry professionals looking to optimize therapeutic efficacy. With its established safety profile and effectiveness, Chloramphenicol palmitate remains a significant compound in the pharmaceutical industry, particularly in formulations aimed at improving patient compliance.

Synonyms
Chloramphenicol α-palmitate
CAS Number
530-43-8
Purity
98 - 102% (Assay by titration, on dry basis)
Grade
meets BP specifications
Molecular Formula
C27H42Cl2N2O6
Molecular Weight
561.5
MDL Number
MFCD00083597
PubChem ID
10736
Melting Point
87 - 95 °C
Appearance
White or almost white unctuous powder
Optical Rotation
[a]20D = 22.5 - 25.5 º
Conditions
Store at 0-8°C
General Information
Synonyms
Chloramphenicol α-palmitate
CAS Number
530-43-8
Purity
98 - 102% (Assay by titration, on dry basis)
Grade
meets BP specifications
Molecular Formula
C27H42Cl2N2O6
Molecular Weight
561.5
MDL Number
MFCD00083597
PubChem ID
10736
Melting Point
87 - 95 °C
Appearance
White or almost white unctuous powder
Optical Rotation
[a]20D = 22.5 - 25.5 º
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

Chloramphenicol palmitate is widely utilized in research focused on

  • Pharmaceutical Development: This compound is often used in the formulation of oral medications, especially for pediatric patients, due to its palmitate ester form which enhances solubility and absorption.
  • Antibiotic Research: It serves as a model compound in studies aimed at understanding antibiotic resistance mechanisms, helping researchers develop more effective treatments.
  • Veterinary Medicine: Chloramphenicol palmitate is used in veterinary applications to treat bacterial infections in animals, providing a crucial alternative when other antibiotics are ineffective.
  • Drug Delivery Systems: The compound is explored in the development of novel drug delivery systems, allowing for targeted release and improved therapeutic outcomes.
  • Analytical Chemistry: It is employed in analytical methods to quantify chloramphenicol levels in biological samples, ensuring safety and compliance in pharmaceutical manufacturing.

Citations