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Catalog Number:
00286
CAS Number:
7365-44-8
N-tris(Hydroxymethyl)methyl-2-aminoethane-sulfonic acid
Purity:
≥ 99% (Assay by titration)
Synonym(s):
TES, 2-[(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]ethanesulfonicacid
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Product Information

N-tris(Hydroxymethyl)methyl-2-aminoethane-sulfonic acid, commonly referred to as TES, is a versatile buffering agent widely utilized in biological and biochemical research. This compound is particularly valued for its ability to maintain a stable pH in various experimental conditions, making it essential for cell culture, protein purification, and enzyme assays. Its unique structure allows for effective buffering in the physiological pH range, which is crucial for maintaining the integrity of biological samples and reactions. Researchers appreciate TES for its low toxicity and minimal interference with biological processes, ensuring that experimental results remain reliable and reproducible.

In addition to its buffering capabilities, TES is also employed in the formulation of various pharmaceutical products and diagnostic reagents. Its compatibility with a wide range of biological systems enhances its utility in both in vitro and in vivo studies. The compound's stability and effectiveness in maintaining pH levels make it a preferred choice over other buffering agents, particularly in sensitive applications such as molecular biology and biochemistry. With its proven track record in enhancing experimental outcomes, TES stands out as a key ingredient for researchers seeking reliable and effective solutions in their work.

Synonyms
TES, 2-[(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]ethanesulfonicacid
CAS Number
7365-44-8
Purity
≥ 99% (Assay by titration)
Molecular Formula
C6H15NO6S
Molecular Weight
229.25
MDL Number
MFCD00007532
PubChem ID
81831
Melting Point
223 - 225 °C
Appearance
White powder
Conditions
Store at RT
General Information
Synonyms
TES, 2-[(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]ethanesulfonicacid
CAS Number
7365-44-8
Purity
≥ 99% (Assay by titration)
Molecular Formula
C6H15NO6S
Molecular Weight
229.25
MDL Number
MFCD00007532
PubChem ID
81831
Melting Point
223 - 225 °C
Appearance
White powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N-tris(Hydroxymethyl)methyl-2-aminoethane-sulfonic acid is widely utilized in research focused on:

  • Biological Buffering: This compound serves as an effective buffering agent in biological and biochemical research, maintaining pH stability in various experiments, which is crucial for enzyme activity and cellular processes.
  • Cell Culture Media: It is commonly used in cell culture media formulations, providing a stable environment for cell growth and ensuring optimal conditions for cellular metabolism and function.
  • Pharmaceutical Formulations: The chemical is incorporated into drug formulations to enhance solubility and stability, making it valuable in the development of effective medications.
  • Protein Purification: In protein biochemistry, it aids in the purification processes by stabilizing proteins during extraction and chromatography, improving yield and activity of the target proteins.
  • Research on Enzyme Kinetics: This compound is utilized in studies involving enzyme kinetics, allowing researchers to accurately measure enzyme activity under controlled pH conditions, which is essential for understanding metabolic pathways.

Citations