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Catalog Number:
37620
CAS Number:
41294-56-8
Alfacalcidol
Purity:
≥ 95% (HPLC)
Synonym(s):
1a-Hydroxyvitamin D3, 1α-Hydroxycholecalciferol
Hazmat
Documents
$259.39 /10MG
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Product Information

Alfacalcidol is a potent active form of vitamin D, primarily utilized in the management of various bone-related disorders. This compound plays a crucial role in calcium and phosphate metabolism, making it essential for maintaining healthy bone density and structure. Alfacalcidol is particularly beneficial in treating conditions such as osteoporosis, renal osteodystrophy, and hypoparathyroidism, where it aids in the regulation of calcium levels in the body. Its unique ability to enhance intestinal absorption of calcium and promote bone mineralization makes it a valuable asset in both clinical and research settings.

In addition to its therapeutic applications, Alfacalcidol is also explored in the field of nutritional supplementation, especially for individuals with limited sun exposure or those with specific dietary restrictions. Researchers appreciate its effectiveness in improving bone health and its potential to reduce the risk of fractures in at-risk populations. With its favorable safety profile and efficacy, Alfacalcidol stands out as a preferred choice for healthcare professionals seeking to optimize patient outcomes in bone health management.

Synonyms
1a-Hydroxyvitamin D3, 1α-Hydroxycholecalciferol
CAS Number
41294-56-8
Purity
≥ 95% (HPLC)
Molecular Formula
C27H44O2
Molecular Weight
400.65
MDL Number
MFCD00868328
PubChem ID
2091
Melting Point
134 - 138 ?C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = 34 - 38 ° (C=0.3 in CHCL3)
Conditions
Store at < -20 °C
General Information
Synonyms
1a-Hydroxyvitamin D3, 1α-Hydroxycholecalciferol
CAS Number
41294-56-8
Purity
≥ 95% (HPLC)
Molecular Formula
C27H44O2
Molecular Weight
400.65
MDL Number
MFCD00868328
PubChem ID
2091
Melting Point
134 - 138 ?C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = 34 - 38 ° (C=0.3 in CHCL3)
Conditions
Store at < -20 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Alfacalcidol is widely utilized in research focused on:

  • Bone Health: It plays a crucial role in the treatment of osteoporosis and other bone-related disorders by enhancing calcium absorption, making it essential for healthcare professionals in orthopedics and geriatrics.
  • Chronic Kidney Disease: Alfacalcidol is often prescribed to manage mineral and bone disorders in patients with chronic kidney disease, helping to maintain proper calcium and phosphate balance.
  • Vitamin D Deficiency: This compound is effective in treating vitamin D deficiency, particularly in populations at risk, such as the elderly or those with limited sun exposure, thus improving overall health outcomes.
  • Endocrinology Research: It is used in studies related to hormonal regulation and metabolism, providing insights into the effects of vitamin D analogs on various endocrine disorders.
  • Pharmaceutical Development: Alfacalcidol serves as a key ingredient in the formulation of various supplements and medications, offering advantages over traditional vitamin D due to its rapid conversion to active metabolites.

Citations