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Catalog Number:
39255
CAS Number:
34157-83-0
Celastrol
Purity:
≥ 98% (HPLC)
Synonym(s):
Tripterin, 10-Hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-picene-2-carboxylicacid
Documents
$60.00 /5MG
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Product Information

Celastrol is a naturally occurring triterpenoid compound extracted from the roots of Tripterygium wilfordii, a traditional Chinese medicinal plant. This compound is recognized for its diverse biological activities, including anti-inflammatory, antioxidant, and anticancer properties. Researchers have shown that Celastrol can inhibit the growth of various cancer cell lines, making it a promising candidate for cancer therapy. Additionally, its ability to modulate the immune response positions it as a potential treatment for autoimmune diseases.

In industrial applications, Celastrol is being explored for its potential in drug development and as a lead compound in the formulation of novel therapeutics. Its unique structure and mechanism of action provide significant advantages over similar compounds, particularly in targeting specific pathways involved in disease progression. With ongoing research, Celastrol holds great promise for advancing therapeutic strategies in oncology and immunology, making it a valuable addition to any researcher's toolkit.

Synonyms
Tripterin, 10-Hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-picene-2-carboxylicacid
CAS Number
34157-83-0
Purity
≥ 98% (HPLC)
Molecular Formula
C29H38O4
Molecular Weight
450.62
MDL Number
MFCD03424073
PubChem ID
4274774
Melting Point
202 - 204 °C (Lit.)
Appearance
Orange red powder
Optical Rotation
[a]20D = -123 to -122 ° (C = 0.1 in CHCl3) (Lit.)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Tripterin, 10-Hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-picene-2-carboxylicacid
CAS Number
34157-83-0
Purity
≥ 98% (HPLC)
Molecular Formula
C29H38O4
Molecular Weight
450.62
MDL Number
MFCD03424073
PubChem ID
4274774
Melting Point
202 - 204 °C (Lit.)
Appearance
Orange red powder
Optical Rotation
[a]20D = -123 to -122 ° (C = 0.1 in CHCl3) (Lit.)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Celastrol is widely utilized in research focused on various applications that benefit multiple industries.

  • Anti-inflammatory Treatments: Celastrol has shown promise in reducing inflammation, making it a candidate for developing new anti-inflammatory drugs. This is particularly beneficial in treating chronic conditions like arthritis.
  • Cancer Research: Studies indicate that celastrol may inhibit tumor growth and induce apoptosis in cancer cells. This application is crucial for researchers in oncology looking for novel therapeutic agents.
  • Metabolic Disorders: Celastrol has been explored for its potential to improve insulin sensitivity and reduce obesity-related complications. This application is relevant for pharmaceutical companies targeting diabetes and metabolic syndrome.
  • Neuroprotective Effects: Research suggests that celastrol may protect neurons from damage, offering potential in developing treatments for neurodegenerative diseases like Alzheimer’s and Parkinson’s.
  • Natural Pest Control: With its insecticidal properties, celastrol is being investigated as a natural pesticide, providing an eco-friendly alternative for agricultural applications.

Citations