Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
39206
CAS Number:
17673-25-5
Phorbol
Purity:
≥ 98% (HPLC)
Documents
$152.33 /5MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Phorbol is a naturally occurring compound known for its diverse biological activities and significant applications in research and industry. This tetracyclic diterpene is primarily recognized for its role as a tumor promoter and its ability to activate protein kinase C (PKC), making it a valuable tool in cancer research. Researchers utilize Phorbol to study cell signaling pathways, particularly those involved in cell growth and differentiation. Its unique structure allows it to mimic diacylglycerol, a key molecule in cellular signaling, providing insights into various physiological processes.

In addition to its research applications, Phorbol has potential uses in the development of therapeutic agents. Its ability to modulate immune responses and influence inflammation positions it as a candidate for further exploration in pharmacology. The compound's distinctive properties, including its hydrophilic and lipophilic characteristics, enhance its versatility in formulations. Phorbol's relevance extends to the fields of biochemistry and pharmacology, where it serves as a critical reagent for understanding complex biological mechanisms and developing novel therapeutic strategies.

CAS Number
17673-25-5
Purity
≥ 98% (HPLC)
Molecular Formula
C20H28O6
Molecular Weight
364.44
MDL Number
MFCD00065450
PubChem ID
290670
Melting Point
251 °C (dec.)
Appearance
White, orange or green crystalline powder
Optical Rotation
[α]20D = 93 ° (C = 1 in H2O)
Conditions
Store at ≤ -10 °C
General Information
CAS Number
17673-25-5
Purity
≥ 98% (HPLC)
Molecular Formula
C20H28O6
Molecular Weight
364.44
MDL Number
MFCD00065450
PubChem ID
290670
Melting Point
251 °C (dec.)
Appearance
White, orange or green crystalline powder
Optical Rotation
[α]20D = 93 ° (C = 1 in H2O)
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Phorbol is widely utilized in research focused on:

  • Cancer Research: Phorbol esters are known for their role in promoting tumor growth in certain cancer models, making them valuable tools for studying cancer biology and testing potential therapeutic agents.
  • Signal Transduction Studies: This compound acts as a potent activator of protein kinase C (PKC), which is crucial in cell signaling pathways. Researchers use it to investigate cellular responses and signaling mechanisms.
  • Inflammation Research: Phorbol is often employed in studies related to inflammation, helping scientists understand the underlying mechanisms and develop anti-inflammatory drugs.
  • Pharmaceutical Development: Due to its biological activity, phorbol derivatives are explored for their potential in developing new drugs, particularly in oncology and immunology.
  • Neuroscience Applications: Researchers utilize phorbol to study its effects on neuronal signaling and plasticity, contributing to our understanding of neurodegenerative diseases and cognitive functions.

Citations