Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
39195
CAS Number:
4759-48-2
13-cis-Retinoic acid
Purity:
≥ 97% (Assay by titration)(HPLC)
Synonym(s):
(2Z,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoicacid, Isotretinoin
Documents
$48.27 /100MG
Pack Size Availability Price
Request Bulk Quote
Product Information

13-cis-Retinoic acid, also known as Isotretinoin, is a powerful derivative of Vitamin A that has gained prominence in the pharmaceutical industry, particularly in the treatment of severe acne and other skin disorders. This compound is recognized for its ability to regulate skin cell production and reduce oil gland activity, making it an essential ingredient in dermatological therapies. Its unique structure allows it to penetrate the skin effectively, promoting cellular turnover and preventing the formation of acne lesions. Additionally, 13-cis-Retinoic acid has shown potential in the treatment of certain cancers, such as acute promyelocytic leukemia, by inducing differentiation in malignant cells.

Researchers and industry professionals value 13-cis-Retinoic acid for its multifaceted applications, which extend beyond dermatology to include oncology and cosmetic formulations. Its efficacy in reducing scarring and improving skin texture makes it a sought-after component in anti-aging products. With a well-established safety profile and a wealth of clinical data supporting its use, 13-cis-Retinoic acid remains a vital compound in both therapeutic and cosmetic applications, offering significant benefits to patients and consumers alike.

Synonyms
(2Z,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoicacid, Isotretinoin
CAS Number
4759-48-2
Purity
≥ 97% (Assay by titration)(HPLC)
Molecular Formula
C20H28O2
Molecular Weight
300.44
MDL Number
MFCD00079542
PubChem ID
5538
Melting Point
175 °C
Appearance
Orange to brown crystalline powder
Conditions
Store at -10 °C
General Information
Synonyms
(2Z,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoicacid, Isotretinoin
CAS Number
4759-48-2
Purity
≥ 97% (Assay by titration)(HPLC)
Molecular Formula
C20H28O2
Molecular Weight
300.44
MDL Number
MFCD00079542
PubChem ID
5538
Melting Point
175 °C
Appearance
Orange to brown crystalline powder
Conditions
Store at -10 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

13-cis-Retinoic acid is widely utilized in research focused on:

  • Treatment of Acne: This compound is a key ingredient in acne medications, helping to reduce severe acne by regulating skin cell turnover and decreasing oil production.
  • Psoriasis Management: It is effective in treating psoriasis, a chronic skin condition, by promoting skin cell differentiation and reducing inflammation.
  • Cancer Research: Researchers explore its role in cancer therapy, particularly in treating certain types of leukemia and neuroblastoma, due to its ability to influence cell growth and differentiation.
  • Vision Health: As a derivative of vitamin A, it plays a crucial role in vision, and is studied for its potential in preventing vision-related disorders.
  • Dermatological Studies: Its properties are investigated in various dermatological studies, providing insights into skin health and the effects of retinoids on aging.

Citations