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Catalog Number:
38732
CAS Number:
25122-57-0
Clobetasone butyrate
Purity:
≥ 98% (HPLC)
Synonym(s):
21-Chloro-9-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,11,20-trione 17-butyrate
Documents
$39.56 /50MG
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Product Information

Clobetasone butyrate is a potent synthetic corticosteroid known for its anti-inflammatory and immunosuppressive properties. This compound is widely utilized in dermatological formulations, particularly in the treatment of various skin conditions such as eczema, psoriasis, and dermatitis. Its effectiveness stems from its ability to reduce inflammation and alleviate itching, making it a preferred choice for topical applications. Clobetasone butyrate is characterized by its favorable safety profile and low systemic absorption, which minimizes the risk of side effects commonly associated with stronger corticosteroids.

In addition to its dermatological uses, Clobetasone butyrate has potential applications in research settings, particularly in studies focused on inflammation and immune response. Its unique chemical structure allows for targeted action, providing researchers with a valuable tool for exploring corticosteroid mechanisms and developing new therapeutic strategies. The compound's versatility and efficacy make it an essential ingredient in both clinical and research environments, offering significant benefits to healthcare professionals and researchers alike.

Synonyms
21-Chloro-9-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,11,20-trione 17-butyrate
CAS Number
25122-57-0
Purity
≥ 98% (HPLC)
Molecular Formula
C26H32ClFO5
Molecular Weight
478.99
MDL Number
MFCD00133196
PubChem ID
2792
Melting Point
177 - 181 ?C
Appearance
White to off-white crystalline powder
Optical Rotation
[α]20D = 137 - 142 ° (C = 1 in CHCl3)
Conditions
Store at 0 - 10 °C
General Information
Synonyms
21-Chloro-9-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,11,20-trione 17-butyrate
CAS Number
25122-57-0
Purity
≥ 98% (HPLC)
Molecular Formula
C26H32ClFO5
Molecular Weight
478.99
MDL Number
MFCD00133196
PubChem ID
2792
Melting Point
177 - 181 ?C
Appearance
White to off-white crystalline powder
Optical Rotation
[α]20D = 137 - 142 ° (C = 1 in CHCl3)
Conditions
Store at 0 - 10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Clobetasone butyrate is widely utilized in research focused on

  • Dermatology: This compound is commonly used in topical formulations to treat inflammatory skin conditions such as eczema and psoriasis, providing effective relief due to its anti-inflammatory properties.
  • Pharmaceutical Development: It serves as a key ingredient in the formulation of corticosteroid medications, allowing for the development of products that manage various allergic reactions and autoimmune disorders.
  • Veterinary Medicine: Clobetasone butyrate is also applied in veterinary treatments, helping to alleviate skin conditions in animals, ensuring their comfort and health.
  • Research on Inflammation: Researchers utilize this compound to study its effects on inflammatory pathways, contributing to the understanding of chronic inflammatory diseases and potential new therapies.
  • Cosmetic Industry: Its anti-inflammatory properties make it a valuable addition to cosmetic products aimed at reducing skin irritation and promoting skin health, appealing to consumers seeking gentle skincare solutions.

Citations