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Catalog Number:
38040
CAS Number:
595-33-5
Megestrol acetate
Purity:
≥ 96% (HPLC)
Synonym(s):
Megestrol 17-acetate, 17a-Hydroxy-6-methyl-4,6-pregnadiene-3,20-dione 17-acetate
Documents
$98.65 /1G
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Product Information

Megestrol acetate is a synthetic progestin that plays a crucial role in various therapeutic applications, particularly in the management of hormone-related conditions. This compound is widely recognized for its effectiveness in treating anorexia, cachexia, and significant weight loss in patients with cancer or AIDS. Its ability to stimulate appetite and promote weight gain makes it a valuable option in palliative care settings. Additionally, megestrol acetate is utilized in hormone replacement therapy and as part of treatment regimens for certain types of breast and endometrial cancers, showcasing its versatility in oncology.

With its unique structure, megestrol acetate offers advantages over other progestins, including a favorable side effect profile and enhanced potency. Researchers and healthcare professionals appreciate its role in improving the quality of life for patients facing severe weight loss and its potential in hormone-sensitive cancers. As a trusted compound in both clinical and research settings, megestrol acetate continues to be a vital tool in the fight against debilitating conditions.

Synonyms
Megestrol 17-acetate, 17a-Hydroxy-6-methyl-4,6-pregnadiene-3,20-dione 17-acetate
CAS Number
595-33-5
Purity
≥ 96% (HPLC)
Molecular Formula
C24H32O4
Molecular Weight
384.52
MDL Number
MFCD00056470
PubChem ID
4048
Melting Point
213 - 220 ?C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]D20 = 9 - 13 ° (C=2 in CHCl3)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Megestrol 17-acetate, 17a-Hydroxy-6-methyl-4,6-pregnadiene-3,20-dione 17-acetate
CAS Number
595-33-5
Purity
≥ 96% (HPLC)
Molecular Formula
C24H32O4
Molecular Weight
384.52
MDL Number
MFCD00056470
PubChem ID
4048
Melting Point
213 - 220 ?C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]D20 = 9 - 13 ° (C=2 in CHCl3)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Megestrol acetate is widely utilized in research focused on:

  • Appetite Stimulation: Commonly used in patients with severe weight loss due to chronic illnesses, it helps to stimulate appetite and promote weight gain, making it valuable in oncology and geriatrics.
  • Hormonal Therapy: Employed in the treatment of hormone-sensitive cancers, particularly breast and endometrial cancers, it acts as a progestin, providing an alternative to traditional therapies.
  • Endometriosis Management: It is effective in managing symptoms of endometriosis by suppressing the growth of endometrial tissue, offering relief to patients suffering from this painful condition.
  • Research in Reproductive Health: Used in studies exploring hormonal regulation and reproductive health, it aids researchers in understanding the mechanisms of hormonal therapies and their effects on various conditions.
  • Clinical Trials: Frequently involved in clinical trials assessing new treatment protocols for weight management and cancer therapies, providing critical data that can lead to improved patient outcomes.

Citations