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Catalog Number:
32405
CAS Number:
71-63-6
Digitoxin
Purity:
≥ 92% (HPLC)
Synonym(s):
5β,20(22)-Cardenolide-3β,14-diol-3-(O-2,6-dideoxy-β-D-ribo-hexopyranosyl-[1→4]-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-[1→4]-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy, Digitalin
Hazmat
Documents
$58.39 /100MG
Pack Size Availability Price
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Product Information

Digitoxin is a potent cardiac glycoside derived from the leaves of the Digitalis plant, primarily used in the treatment of heart conditions such as atrial fibrillation and heart failure. This compound works by increasing the force of heart contractions and regulating heart rhythm, making it invaluable in cardiology. Its unique structure allows for effective binding to the sodium-potassium ATPase enzyme, which enhances cardiac output and improves symptoms in patients with heart diseases.

In addition to its therapeutic applications, Digitoxin is also utilized in pharmacological research to study its effects on cardiac function and its potential interactions with other medications. Its long half-life allows for less frequent dosing, which can improve patient compliance compared to other similar compounds. Researchers and healthcare professionals appreciate Digitoxin for its established efficacy and the depth of clinical data supporting its use, making it a reliable choice in both clinical and research settings.

Synonyms
5β,20(22)-Cardenolide-3β,14-diol-3-(O-2,6-dideoxy-β-D-ribo-hexopyranosyl-[1→4]-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-[1→4]-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy, Digitalin
CAS Number
71-63-6
Purity
≥ 92% (HPLC)
Molecular Formula
C41H64O13
Molecular Weight
764.94
MDL Number
MFCD00003686
PubChem ID
3061
Melting Point
240 ?C (dec.)
Appearance
White to off-white powder
Optical Rotation
[a]20/D= +160 to +18.5° (C=2 in CHCl3(stabilized with Ethanol))
Conditions
Store at RT
General Information
Synonyms
5β,20(22)-Cardenolide-3β,14-diol-3-(O-2,6-dideoxy-β-D-ribo-hexopyranosyl-[1→4]-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-[1→4]-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy, Digitalin
CAS Number
71-63-6
Purity
≥ 92% (HPLC)
Molecular Formula
C41H64O13
Molecular Weight
764.94
MDL Number
MFCD00003686
PubChem ID
3061
Melting Point
240 ?C (dec.)
Appearance
White to off-white powder
Optical Rotation
[a]20/D= +160 to +18.5° (C=2 in CHCl3(stabilized with Ethanol))
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Digitoxin is widely utilized in research focused on:

  • Cardiovascular Medicine: It is primarily used to treat heart conditions such as atrial fibrillation and heart failure by increasing the force of heart contractions, which can improve overall heart function.
  • Pharmacological Studies: Researchers use digitoxin to study its effects on cardiac glycosides, helping to understand its mechanism of action and potential interactions with other medications.
  • Clinical Trials: It plays a role in clinical trials aimed at evaluating new treatments for heart diseases, providing a benchmark for efficacy and safety in comparison to newer compounds.
  • Veterinary Medicine: Digitoxin is also applied in veterinary practices for treating heart conditions in animals, showcasing its versatility across species.
  • Historical Research: Its historical use in traditional medicine provides insights into the development of modern pharmacology and the evolution of heart disease treatments.

Citations