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Catalog Number:
38945
CAS Number:
67254-28-8
1,2-Dioleoyl-sn-glycero-3-phospho-rac-(1-glycerol) sodium salt
Purity:
≥ 98% (Assay by titration)
Synonym(s):
Sodium (R-2,3-bis(oleoyloxy)propyl (2,3-dihydroxypropyl)phosphate, Dioleoylphosphatidylglycerol sodium salt
Documents
$349.62 /250MG
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Product Information

1,2-Dioleoyl-sn-glycero-3-phospho-rac-(1-glycerol) sodium salt is a versatile phospholipid that plays a crucial role in various biochemical applications. This compound is recognized for its unique amphiphilic properties, making it an ideal candidate for use in drug delivery systems, particularly in liposomal formulations. Its ability to form stable lipid bilayers enhances the encapsulation of hydrophilic drugs, improving bioavailability and therapeutic efficacy. Additionally, this phospholipid is widely utilized in the development of nanocarriers for targeted therapy, allowing for precise delivery of active pharmaceutical ingredients to specific tissues or cells.

In research settings, 1,2-Dioleoyl-sn-glycero-3-phospho-rac-(1-glycerol) sodium salt is employed in the formulation of liposomes and micelles, facilitating studies in cellular uptake and membrane interactions. Its biocompatibility and low toxicity profile make it suitable for applications in both in vitro and in vivo studies. Furthermore, this compound is increasingly being explored for its potential in vaccine development, where it can enhance immune responses by serving as an adjuvant. With its diverse applications and significant benefits, this phospholipid is a valuable asset for researchers and industry professionals alike.

Synonyms
Sodium (R-2,3-bis(oleoyloxy)propyl (2,3-dihydroxypropyl)phosphate, Dioleoylphosphatidylglycerol sodium salt
CAS Number
67254-28-8
Purity
≥ 98% (Assay by titration)
Molecular Formula
C42H78NaO10P
Molecular Weight
797.04
PubChem ID
74088308
Appearance
White to almost white powder to crystal
Optical Rotation
[α]20D = 9 ° (C=2, EtOH)
Conditions
Store at ≤ -10 °C
General Information
Synonyms
Sodium (R-2,3-bis(oleoyloxy)propyl (2,3-dihydroxypropyl)phosphate, Dioleoylphosphatidylglycerol sodium salt
CAS Number
67254-28-8
Purity
≥ 98% (Assay by titration)
Molecular Formula
C42H78NaO10P
Molecular Weight
797.04
PubChem ID
74088308
Appearance
White to almost white powder to crystal
Optical Rotation
[α]20D = 9 ° (C=2, EtOH)
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

1,2-Dioleoyl-sn-glycero-3-phospho-rac-(1-glycerol) sodium salt is widely utilized in research focused on:

  • Drug Delivery Systems: This compound is commonly used in the formulation of liposomes, which are tiny vesicles that can encapsulate drugs, improving their delivery and efficacy in targeted therapies.
  • Biotechnology: It serves as a key component in the development of biomaterials for tissue engineering, helping to create scaffolds that support cell growth and tissue regeneration.
  • Cosmetic Formulations: The compound is incorporated into skincare products due to its emulsifying properties, enhancing texture and stability while providing moisturizing benefits.
  • Food Industry: It is utilized as an emulsifier in food products, improving the consistency and shelf-life of various items, such as dressings and sauces.
  • Research Applications: In laboratory settings, it is used to study membrane dynamics and lipid interactions, providing insights into cellular processes and potential therapeutic targets.

Citations