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Catalog Number:
31110
CAS Number:
4004-05-1
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
Purity:
≥ 99% (Assay)
Synonym(s):
2-Aminoethyl (R)-2,3-bis(oleoyloxy)propyl hydrogenphosphate, 1,2-Di(9Z-Octadecenoyl)-sn-glycero-3-phosphoethanolamine, Dioleoyl phosphatidylethanolamine, DOPE
Documents
$85.60 /100MG
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Product Information

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine is a phospholipid that plays a crucial role in various biological and industrial applications. This compound is recognized for its ability to form lipid bilayers, making it an essential component in the formulation of liposomes and other drug delivery systems. Its unique structure allows for enhanced membrane fluidity and stability, which is particularly beneficial in pharmaceutical formulations aimed at improving the bioavailability of therapeutic agents. Researchers often utilize this phospholipid in studies related to cell membrane dynamics, signal transduction, and the development of targeted drug delivery systems.

In addition to its applications in drug delivery, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine is also employed in the creation of biosensors and as a stabilizing agent in various biochemical assays. Its compatibility with a wide range of biomolecules makes it a versatile choice for researchers looking to explore cellular interactions and membrane biology. The compound's ability to facilitate the incorporation of proteins and nucleic acids into lipid-based systems further enhances its utility in biotechnology and pharmaceutical research.

Synonyms
2-Aminoethyl (R)-2,3-bis(oleoyloxy)propyl hydrogenphosphate, 1,2-Di(9Z-Octadecenoyl)-sn-glycero-3-phosphoethanolamine, Dioleoyl phosphatidylethanolamine, DOPE
CAS Number
4004-05-1
Purity
≥ 99% (Assay)
Molecular Formula
C41H78NO8P
Molecular Weight
744.03
MDL Number
MFCD16621009
PubChem ID
108229
Appearance
Yellowish to light yellow or white waxy solid
Conditions
Store at ≤ -20 °C
General Information
Synonyms
2-Aminoethyl (R)-2,3-bis(oleoyloxy)propyl hydrogenphosphate, 1,2-Di(9Z-Octadecenoyl)-sn-glycero-3-phosphoethanolamine, Dioleoyl phosphatidylethanolamine, DOPE
CAS Number
4004-05-1
Purity
≥ 99% (Assay)
Molecular Formula
C41H78NO8P
Molecular Weight
744.03
MDL Number
MFCD16621009
PubChem ID
108229
Appearance
Yellowish to light yellow or white waxy solid
Conditions
Store at ≤ -20 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine is widely utilized in research focused on:

  • Drug Delivery Systems: This compound is often used in the formulation of liposomes, which are tiny vesicles that can encapsulate drugs. This application is crucial in targeted drug delivery, enhancing the efficacy of treatments while minimizing side effects.
  • Vaccine Development: It plays a significant role in the development of lipid-based vaccines, helping to improve immune responses. This is particularly important in the fight against infectious diseases, including emerging viral threats.
  • Cell Membrane Studies: Researchers utilize this phospholipid to create model membranes for studying cellular processes. This helps in understanding membrane dynamics and interactions, which is vital for drug design and cell biology.
  • Biotechnology Applications: In biotechnology, it is used in the formulation of nanoparticles for gene delivery. This application is essential for gene therapy, allowing for the safe and effective transfer of genetic material into cells.
  • Cosmetic Formulations: The compound is also found in cosmetic products, where it acts as an emulsifier and skin-conditioning agent, providing stability and enhancing the texture of creams and lotions.

Citations