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Catalog Number:
29749
CAS Number:
1069-79-0
1,2-Distearoyl-sn-glycero-3-phosphoethanolamine
Purity:
≥ 98% (Assay)
Synonym(s):
1,2-Dioctadecanoyl-sn-glycero-3-phosphoethanolamine, 3-sn-Phosphatidylethanolamine
Documents
$55.00 /100MG
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Product Information

1,2-Distearoyl-sn-glycero-3-phosphoethanolamine is a phospholipid that plays a crucial role in various biotechnological and pharmaceutical applications. This compound is particularly valued for its ability to form stable lipid bilayers, making it an essential component in the formulation of liposomes and other drug delivery systems. Its unique structure allows for enhanced encapsulation of therapeutic agents, improving bioavailability and targeting efficiency. Researchers often utilize this compound in the development of vaccines and gene therapy, where it aids in the effective delivery of nucleic acids and proteins into cells.

Additionally, 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine is recognized for its biocompatibility and low toxicity, making it suitable for use in various biomedical applications. Its properties enable the formulation of advanced drug delivery systems that can provide controlled release and improved therapeutic outcomes. This compound stands out among similar phospholipids due to its specific fatty acid composition, which contributes to its stability and performance in complex formulations.

Synonyms
1,2-Dioctadecanoyl-sn-glycero-3-phosphoethanolamine, 3-sn-Phosphatidylethanolamine
CAS Number
1069-79-0
Purity
≥ 98% (Assay)
Molecular Formula
C41H82NO8P
Molecular Weight
748.07
MDL Number
MFCD00036777
PubChem ID
102547
Melting Point
194 - 198 °C (Lit.)
Appearance
White to off-white solid
Optical Rotation
[a]D20 = 5 ± 2 º (Lit.)
Conditions
Store at -20 °C
General Information
Synonyms
1,2-Dioctadecanoyl-sn-glycero-3-phosphoethanolamine, 3-sn-Phosphatidylethanolamine
CAS Number
1069-79-0
Purity
≥ 98% (Assay)
Molecular Formula
C41H82NO8P
Molecular Weight
748.07
MDL Number
MFCD00036777
PubChem ID
102547
Melting Point
194 - 198 °C (Lit.)
Appearance
White to off-white solid
Optical Rotation
[a]D20 = 5 ± 2 º (Lit.)
Conditions
Store at -20 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

1,2-Distearoyl-sn-glycero-3-phosphoethanolamine is widely utilized in research focused on:

  • Drug Delivery Systems: This compound is a key component in liposomes, which are used to encapsulate drugs for targeted delivery. This enhances the bioavailability of pharmaceuticals, making treatments more effective.
  • Vaccine Formulations: It plays a crucial role in the development of lipid nanoparticles for mRNA vaccines, improving stability and immune response, which is vital in the fight against infectious diseases.
  • Cell Membrane Studies: Researchers use it to create model membranes that mimic biological systems, aiding in the study of membrane dynamics and protein interactions.
  • Cosmetic Applications: This compound is incorporated into skincare products for its emulsifying properties, enhancing texture and stability while providing skin benefits.
  • Biotechnology: It is used in the formulation of gene delivery systems, facilitating the transport of genetic material into cells, which is essential for gene therapy and genetic engineering applications.

Citations