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Catalog Number:
42177
CAS Number:
136831-49-7
Tyrphostin RG 14620
Purity:
≥ 98% (HPLC)
Synonym(s):
3-(3,5-Dichlorophenyl)-2-(pyridin-3-yl)acrylonitrile
Documents
$328.99 /25MG
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Product Information

Tyrphostin RG 14620 is a potent chemical compound recognized for its role as a selective inhibitor of receptor tyrosine kinases, particularly in cancer research. This compound is characterized by its unique structure, featuring a pyridine ring and dichlorophenyl moiety, which contribute to its biological activity. Tyrphostin RG 14620 has shown promise in various studies for its ability to inhibit cell proliferation and induce apoptosis in tumor cells, making it a valuable tool for researchers exploring targeted cancer therapies. Its specificity towards certain kinases allows for more precise interventions in signaling pathways, potentially leading to fewer side effects compared to broader-spectrum inhibitors.

In addition to its applications in oncology, Tyrphostin RG 14620 is also being investigated for its effects on other diseases where receptor tyrosine kinases play a critical role, such as diabetes and neurodegenerative disorders. Researchers appreciate its ability to provide insights into the mechanisms of disease progression and treatment responses. With its growing relevance in both academic and pharmaceutical research, Tyrphostin RG 14620 stands out as a compound with significant potential for advancing therapeutic strategies.

Synonyms
3-(3,5-Dichlorophenyl)-2-(pyridin-3-yl)acrylonitrile
CAS Number
136831-49-7
Purity
≥ 98% (HPLC)
Molecular Formula
C14H8Cl2N2
Molecular Weight
275.13
MDL Number
MFCD00236445
PubChem ID
5061
Melting Point
155 °C (Lit.)
Appearance
White to light yellow powder
Conditions
Store at ≤ -10 °C
General Information
Synonyms
3-(3,5-Dichlorophenyl)-2-(pyridin-3-yl)acrylonitrile
CAS Number
136831-49-7
Purity
≥ 98% (HPLC)
Molecular Formula
C14H8Cl2N2
Molecular Weight
275.13
MDL Number
MFCD00236445
PubChem ID
5061
Melting Point
155 °C (Lit.)
Appearance
White to light yellow powder
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Tyrphostin RG 14620 is widely utilized in research focused on:

  • Cancer Research: This compound is known for its ability to inhibit specific tyrosine kinases, making it a valuable tool in studying cancer cell signaling pathways and potential treatments.
  • Neuroscience: Researchers use it to explore the role of tyrosine kinases in neuronal signaling, which can lead to advancements in understanding neurodegenerative diseases.
  • Drug Development: Its properties allow scientists to develop targeted therapies that can minimize side effects compared to traditional chemotherapy, enhancing patient outcomes.
  • Cell Biology: It serves as a critical reagent in experiments designed to dissect cellular processes, particularly those involving growth factor signaling.
  • Pharmaceutical Formulations: The compound's unique structure can be leveraged in creating innovative drug formulations, potentially improving bioavailability and efficacy.

Citations