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Catalog Number:
42166
CAS Number:
161735-79-1
Rasagiline mesylate
Purity:
≥ 98% (HPLC)
Synonym(s):
(R)-N-(2-Propyn-1-yl)-1-indanaminemethanesulfonate, (R)-N-Propargyl-1-indanamine methanesulfonate
Documents
$80.62 /250MG
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Product Information

Rasagiline mesylate is a potent and selective irreversible inhibitor of monoamine oxidase B (MAO-B), primarily used in the treatment of Parkinson's disease. This compound enhances dopaminergic activity in the brain, providing symptomatic relief and improving the quality of life for patients. Its unique mechanism of action allows for a reduction in the metabolism of dopamine, making it particularly beneficial for patients experiencing motor fluctuations. Rasagiline mesylate is often utilized in both monotherapy and as an adjunct to levodopa therapy, showcasing its versatility in managing Parkinson's symptoms effectively.

In addition to its therapeutic applications, Rasagiline mesylate has been explored for its neuroprotective properties, suggesting potential benefits in delaying disease progression. Researchers are investigating its role in various neurological disorders, highlighting its relevance in both clinical and research settings. The compound's favorable pharmacokinetic profile, including its oral bioavailability and long half-life, further supports its use in long-term treatment regimens. With ongoing studies, Rasagiline mesylate continues to demonstrate promise in advancing treatment strategies for neurodegenerative diseases.

Synonyms
(R)-N-(2-Propyn-1-yl)-1-indanaminemethanesulfonate, (R)-N-Propargyl-1-indanamine methanesulfonate
CAS Number
161735-79-1
Purity
≥ 98% (HPLC)
Molecular Formula
C12H13N·CH4O3S
Molecular Weight
267.34
MDL Number
MFCD08460604
PubChem ID
10355621
Melting Point
155 - 159 °C
Appearance
White to off-white powder
Optical Rotation
[α]20D = 20 - 22 ° (C=2 in Ethanol)
Conditions
Store at ≤ -4 °C
General Information
Synonyms
(R)-N-(2-Propyn-1-yl)-1-indanaminemethanesulfonate, (R)-N-Propargyl-1-indanamine methanesulfonate
CAS Number
161735-79-1
Purity
≥ 98% (HPLC)
Molecular Formula
C12H13N·CH4O3S
Molecular Weight
267.34
MDL Number
MFCD08460604
PubChem ID
10355621
Melting Point
155 - 159 °C
Appearance
White to off-white powder
Optical Rotation
[α]20D = 20 - 22 ° (C=2 in Ethanol)
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Rasagiline mesylate is widely utilized in research focused on:

  • Parkinson's Disease Treatment: This compound is primarily used in the management of Parkinson's disease, helping to alleviate symptoms and improve the quality of life for patients.
  • Neuroprotective Studies: Researchers explore its neuroprotective properties, investigating how it may help protect neurons from degeneration, which is crucial for developing new therapies.
  • Combination Therapies: It is often studied in combination with other medications to enhance therapeutic effects, providing insights into more effective treatment regimens.
  • Pharmacokinetic Research: The compound is used to understand its absorption, distribution, metabolism, and excretion, helping to optimize dosing strategies for better patient outcomes.
  • Clinical Trials: Rasagiline mesylate is frequently involved in clinical trials aimed at assessing its efficacy and safety, contributing to the advancement of treatment options for neurodegenerative diseases.

Citations