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Catalog Number:
42147
CAS Number:
127770-45-0
5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate
Purity:
≥ 85%
Documents
$260.69 /100MG
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Product Information

5(6)-Carboxy-2',7'-dichlorofluorescein diacetate is a highly versatile fluorescent dye widely utilized in biological and chemical research. This compound is particularly valued for its ability to permeate cell membranes, making it an excellent choice for cell viability assays and fluorescence microscopy. Its unique structure allows for effective labeling of live cells, enabling researchers to monitor cellular processes in real-time. The compound can be hydrolyzed within cells to release the fluorescent carboxyfluorescein, providing a strong fluorescence signal that enhances detection sensitivity in various applications.

In addition to its use in cell biology, 5(6)-Carboxy-2',7'-dichlorofluorescein diacetate is also employed in flow cytometry and other analytical techniques, where its fluorescent properties facilitate the quantification of cellular characteristics. Researchers appreciate its stability and ease of use, making it a reliable choice for experiments requiring precise fluorescence measurements. This compound stands out for its ability to provide clear, reproducible results, which is essential for advancing scientific understanding in fields such as pharmacology, toxicology, and cellular biology.

CAS Number
127770-45-0
Purity
≥ 85%
Molecular Formula
C25H14Cl2O9
Molecular Weight
529.28
MDL Number
MFCD08459585
Melting Point
210 °C (dec.) (Lit.)
Appearance
Off-white to light orange powder
Conditions
Store at ≤ -10 °C
General Information
CAS Number
127770-45-0
Purity
≥ 85%
Molecular Formula
C25H14Cl2O9
Molecular Weight
529.28
MDL Number
MFCD08459585
Melting Point
210 °C (dec.) (Lit.)
Appearance
Off-white to light orange powder
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5(6)-Carboxy-2',7'-dichlorofluorescein diacetate is widely utilized in research focused on:

  • Cell Viability Assays: This compound is commonly used in fluorescence-based assays to assess cell viability and proliferation, providing researchers with a reliable method to evaluate the effects of drugs or treatments on cell health.
  • Fluorescent Imaging: It serves as a fluorescent marker in microscopy, allowing scientists to visualize cellular processes and structures with high specificity, which is crucial in fields like cell biology and cancer research.
  • Apoptosis Detection: The chemical is effective in detecting apoptosis (programmed cell death) in various cell types, aiding researchers in understanding disease mechanisms and therapeutic responses.
  • Environmental Monitoring: It can be applied in environmental studies to track the uptake and distribution of pollutants in aquatic systems, helping to assess ecosystem health and contamination levels.
  • Drug Delivery Research: The compound is explored in drug delivery systems due to its ability to fluoresce, enabling real-time tracking of drug release and distribution in biological systems.

Citations