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Catalog Number:
38066
CAS Number:
555-57-7
Pargyline
Purity:
≥ 98% (HPLC)
Synonym(s):
N-Methyl-N-(2-propyn-1-yl)benzylamine, N-Methyl-N-propargylbenzylamine
Hazmat
Documents
$35.00 /1G
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Product Information

Pargyline is a potent monoamine oxidase inhibitor (MAOI) primarily utilized in the treatment of hypertension and certain neurological disorders. This compound is recognized for its ability to enhance neurotransmitter levels, particularly dopamine, making it valuable in research related to neurodegenerative diseases such as Parkinson's. Its unique structure allows for selective inhibition of monoamine oxidase B, which is crucial in managing symptoms associated with dopamine depletion.

In addition to its therapeutic applications, Pargyline is also employed in various biochemical studies, particularly in exploring the mechanisms of neurotransmitter regulation and metabolism. Researchers appreciate its role in elucidating the pathways involved in mood regulation and cognitive function. With its specific action and minimal side effects compared to other MAOIs, Pargyline stands out as a preferred choice for both clinical and research settings, offering significant potential for advancing our understanding of neuropharmacology.

Synonyms
N-Methyl-N-(2-propyn-1-yl)benzylamine, N-Methyl-N-propargylbenzylamine
CAS Number
555-57-7
Purity
≥ 98% (HPLC)
Molecular Formula
C11H13N
Molecular Weight
159.23
MDL Number
MFCD00008576
PubChem ID
4688
Density
0.95 (Lit.)
Appearance
Colorless to yellow liquid
Boiling Point
89 - 91 °C/4 mmHg (Lit.)
Refractive Index
n20/D 1.520 (Lit.)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
N-Methyl-N-(2-propyn-1-yl)benzylamine, N-Methyl-N-propargylbenzylamine
CAS Number
555-57-7
Purity
≥ 98% (HPLC)
Molecular Formula
C11H13N
Molecular Weight
159.23
MDL Number
MFCD00008576
PubChem ID
4688
Density
0.95 (Lit.)
Appearance
Colorless to yellow liquid
Boiling Point
89 - 91 °C/4 mmHg (Lit.)
Refractive Index
n20/D 1.520 (Lit.)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Pargyline is widely utilized in research focused on:

  • Neuroprotection: Pargyline is used in studies investigating its potential to protect neurons from damage, particularly in neurodegenerative diseases like Parkinson's. Its ability to inhibit monoamine oxidase (MAO) can help increase levels of neurotransmitters, which is beneficial in maintaining cognitive function.
  • Antidepressant Research: Researchers explore its role as an antidepressant due to its MAO-inhibiting properties. This can lead to enhanced mood and emotional well-being, making it a subject of interest in the development of new antidepressant therapies.
  • Cardiovascular Studies: Pargyline has applications in cardiovascular research, where it is examined for its effects on blood pressure regulation and vascular health, potentially offering benefits in managing hypertension.
  • Pharmaceutical Development: The compound serves as a valuable reference in the synthesis of other pharmaceuticals, particularly those targeting neurological conditions, due to its unique chemical structure and properties.
  • Research on Aging: Pargyline is investigated for its potential effects on aging processes, particularly in extending lifespan in model organisms, which could have implications for age-related health issues.

Citations