Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
37989
CAS Number:
75330-75-5
Lovastatin
Grade:
Meets USP Specification
Purity:
98.5 - 101.0% (Assay on dried basis)
Synonym(s):
Mevinolin, Monacolin K
Documents
$30.00 /5G
Pack Size Availability Price
Request Bulk Quote
Product Information

Lovastatin is a naturally occurring statin that plays a crucial role in the management of cholesterol levels. As a competitive inhibitor of HMG-CoA reductase, it effectively reduces the synthesis of cholesterol in the liver, making it a vital therapeutic agent in the treatment of hyperlipidemia and cardiovascular diseases. Lovastatin is widely recognized for its ability to lower low-density lipoprotein (LDL) cholesterol and triglycerides while potentially increasing high-density lipoprotein (HDL) cholesterol. This compound is particularly beneficial for patients at risk of heart disease, as it not only helps in managing cholesterol levels but also contributes to overall cardiovascular health.

In addition to its primary use in cholesterol management, Lovastatin has shown promise in various research applications, including its potential anti-inflammatory and antioxidant properties. Researchers are exploring its effects on metabolic syndrome and certain types of cancer, highlighting its versatility beyond traditional cholesterol-lowering therapies. Lovastatin's unique mechanism of action and its established safety profile make it a preferred choice for both healthcare professionals and researchers seeking effective solutions for lipid management and related health conditions.

Synonyms
Mevinolin, Monacolin K
CAS Number
75330-75-5
Purity
98.5 - 101.0% (Assay on dried basis)
Grade
Meets USP Specification
Molecular Formula
C24H36O5
Molecular Weight
404.55
MDL Number
MFCD00072164
PubChem ID
3962
Melting Point
178 - 180 °C
Appearance
White to light yellow powder to crystal
Optical Rotation
[a]20D = 324 - 338 ° (C=5 mg/mL in Acetonitrile)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Mevinolin, Monacolin K
CAS Number
75330-75-5
Purity
98.5 - 101.0% (Assay on dried basis)
Grade
Meets USP Specification
Molecular Formula
C24H36O5
Molecular Weight
404.55
MDL Number
MFCD00072164
PubChem ID
3962
Melting Point
178 - 180 °C
Appearance
White to light yellow powder to crystal
Optical Rotation
[a]20D = 324 - 338 ° (C=5 mg/mL in Acetonitrile)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Lovastatin is widely utilized in research focused on:

  • Cholesterol Management: Commonly prescribed to lower LDL cholesterol levels, making it a crucial medication in cardiovascular health.
  • Research on Statins: Used in studies investigating the efficacy and safety of statins, helping to develop better treatment protocols for patients with hyperlipidemia.
  • Anti-Inflammatory Studies: Investigated for its potential anti-inflammatory properties, contributing to research in conditions like arthritis and other inflammatory diseases.
  • Neuroprotective Effects: Explored for its possible benefits in neurodegenerative diseases, such as Alzheimer's, providing insights into new therapeutic avenues.
  • Drug Development: Serves as a model compound in pharmaceutical research for developing new cholesterol-lowering agents with improved efficacy and reduced side effects.

Citations