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Catalog Number:
37884
CAS Number:
93957-55-2
Fluvastatin sodium salt hydrate
Purity:
98 - 102% (Assay on anhydrous basis)
Synonym(s):
(+/-)-(3R*,5S*,6E)-7-[3-(4-Fluorophenyl)-1-(1-methyethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoicacid sodium salt hydrate
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Product Information

Fluvastatin sodium salt hydrate is a potent statin used primarily for the management of hyperlipidemia and the prevention of cardiovascular diseases. This compound functions by inhibiting HMG-CoA reductase, an enzyme crucial for cholesterol synthesis in the liver, thereby effectively lowering LDL cholesterol levels. Its unique structure, featuring a fluorophenyl group, enhances its efficacy and selectivity, making it a preferred choice in clinical settings. Researchers and healthcare professionals appreciate its role in not only reducing cholesterol but also in potentially stabilizing atherosclerotic plaques, which can lead to improved cardiovascular outcomes.

In addition to its primary use in lipid management, Fluvastatin sodium salt hydrate has shown promise in various therapeutic areas, including oncology and neuroprotection, due to its anti-inflammatory properties. Its ability to cross the blood-brain barrier opens avenues for research into its effects on neurodegenerative diseases. With a favorable safety profile and a well-established mechanism of action, this compound stands out as a valuable asset in both pharmaceutical development and clinical practice.

Synonyms
(+/-)-(3R*,5S*,6E)-7-[3-(4-Fluorophenyl)-1-(1-methyethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoicacid sodium salt hydrate
CAS Number
93957-55-2
Purity
98 - 102% (Assay on anhydrous basis)
Molecular Formula
C24H25FNNaO4·xH2O
Molecular Weight
433.46
MDL Number
MFCD00929076
PubChem ID
24906289
Appearance
White to yellowish or brownish yellow powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(+/-)-(3R*,5S*,6E)-7-[3-(4-Fluorophenyl)-1-(1-methyethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoicacid sodium salt hydrate
CAS Number
93957-55-2
Purity
98 - 102% (Assay on anhydrous basis)
Molecular Formula
C24H25FNNaO4·xH2O
Molecular Weight
433.46
MDL Number
MFCD00929076
PubChem ID
24906289
Appearance
White to yellowish or brownish yellow powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fluvastatin sodium salt hydrate is widely utilized in research focused on:

  • Cholesterol Management: This compound is primarily used in the pharmaceutical industry to lower cholesterol levels in patients with hyperlipidemia, helping to reduce the risk of cardiovascular diseases.
  • Clinical Research: It serves as a key subject in clinical trials aimed at understanding its efficacy and safety in various populations, providing valuable data for healthcare professionals.
  • Combination Therapies: Fluvastatin is often studied in combination with other medications to enhance treatment outcomes for patients with heart disease, showcasing its versatility in therapeutic regimens.
  • Mechanistic Studies: Researchers utilize this compound to explore its mechanisms of action at the molecular level, contributing to a deeper understanding of lipid metabolism and its implications in health.
  • Preventive Medicine: It is also applied in preventive strategies for at-risk populations, helping to mitigate the onset of chronic conditions related to high cholesterol levels.

Citations