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Catalog Number:
37648
CAS Number:
86541-74-4
Benazepril hydrochloride
Purity:
≥ 98% (Assay by titration, HPLC)
Synonym(s):
(3S)-3-[(1S)-1-Ethoxycarbonyl-3-phenylpropyl]amino-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-aceticacid hydrochloride
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$259.39 /1G
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Product Information

Benazepril hydrochloride is a potent angiotensin-converting enzyme (ACE) inhibitor widely utilized in the management of hypertension and heart failure. This compound works by relaxing blood vessels, thereby reducing blood pressure and improving blood flow. Its unique structure allows for effective inhibition of the ACE enzyme, making it a preferred choice for healthcare professionals in treating cardiovascular conditions. Additionally, Benazepril hydrochloride is often used in combination therapies, enhancing the efficacy of other antihypertensive agents and providing a comprehensive approach to patient care.

In research settings, Benazepril hydrochloride has demonstrated potential beyond its primary applications, including studies on renal protection and its role in mitigating the effects of diabetic nephropathy. Its favorable pharmacokinetic profile and low incidence of side effects make it an attractive option for long-term treatment plans. With its established efficacy and safety, Benazepril hydrochloride continues to be a vital component in the therapeutic arsenal against cardiovascular diseases, offering significant benefits to both patients and healthcare providers.

Synonyms
(3S)-3-[(1S)-1-Ethoxycarbonyl-3-phenylpropyl]amino-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-aceticacid hydrochloride
CAS Number
86541-74-4
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C24H28N2O5·HCl
Molecular Weight
460.96
MDL Number
MFCD00895734
PubChem ID
13243513
Melting Point
183 °C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = -134 to -140 ° (C=1 in EtOH)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(3S)-3-[(1S)-1-Ethoxycarbonyl-3-phenylpropyl]amino-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-aceticacid hydrochloride
CAS Number
86541-74-4
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C24H28N2O5·HCl
Molecular Weight
460.96
MDL Number
MFCD00895734
PubChem ID
13243513
Melting Point
183 °C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = -134 to -140 ° (C=1 in EtOH)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Benazepril hydrochloride is widely utilized in research focused on

  • Hypertension Treatment: This compound is primarily used in the pharmaceutical industry for managing high blood pressure, offering effective control and reducing the risk of heart-related complications.
  • Heart Failure Management: It is also prescribed for patients with heart failure, helping to improve heart function and enhance quality of life.
  • Kidney Protection: In diabetic patients, benazepril hydrochloride is beneficial for protecting kidney function, thereby reducing the risk of diabetic nephropathy.
  • Research in Cardiovascular Pharmacology: Researchers utilize this compound to study its effects on the cardiovascular system, contributing to the development of new antihypertensive therapies.
  • Combination Therapies: It is often used in combination with other medications, providing a synergistic effect that enhances overall treatment efficacy for various cardiovascular conditions.

Citations