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Catalog Number:
32498
CAS Number:
91421-42-0
Rubitecan
Purity:
≥ 96% (HPLC)
Synonym(s):
9-Nitrocamptothecin, Orathecin
Documents
$127.79 /25MG
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Product Information

Rubitecan is a potent chemical compound recognized for its unique structure and significant applications in the pharmaceutical industry, particularly in cancer treatment. This compound, also known as 9-Nitrocamptothecin, is a derivative of camptothecin and exhibits remarkable antitumor activity by inhibiting topoisomerase I, an enzyme crucial for DNA replication. Researchers and pharmaceutical developers leverage Rubitecan's properties to explore innovative therapies for various cancers, including colorectal and lung cancer, making it a valuable asset in oncology research and drug formulation.

In addition to its therapeutic potential, Rubitecan's unique chemical structure allows for modifications that can enhance its efficacy and reduce side effects, positioning it as a promising candidate for further development in targeted cancer therapies. Its ability to penetrate cellular membranes and selectively target cancer cells underscores its relevance in the ongoing quest for more effective cancer treatments. As researchers continue to investigate its full potential, Rubitecan stands out as a compound with significant promise in advancing cancer therapeutics.

Synonyms
9-Nitrocamptothecin, Orathecin
CAS Number
91421-42-0
Purity
≥ 96% (HPLC)
Molecular Formula
C20H15N3O6
Molecular Weight
393.35
MDL Number
MFCD06656294
PubChem ID
15200290
Melting Point
268 °C
Appearance
Off-white to yellow powder
Conditions
Store at RT
General Information
Synonyms
9-Nitrocamptothecin, Orathecin
CAS Number
91421-42-0
Purity
≥ 96% (HPLC)
Molecular Formula
C20H15N3O6
Molecular Weight
393.35
MDL Number
MFCD06656294
PubChem ID
15200290
Melting Point
268 °C
Appearance
Off-white to yellow powder
Conditions
Store at RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Rubitecan is widely utilized in research focused on:

  • Cancer Treatment: This compound is primarily explored for its potential as an anti-cancer agent, particularly in treating various solid tumors. Its unique structure allows it to interfere with cancer cell proliferation.
  • Pharmaceutical Development: Rubitecan serves as a lead compound in the development of new chemotherapeutic drugs, offering insights into drug design and efficacy in targeting cancer cells.
  • Drug Formulation: In the pharmaceutical industry, it is used in formulating targeted drug delivery systems, enhancing the bioavailability and therapeutic effects of cancer treatments.
  • Research in Drug Resistance: Researchers study Rubitecan to understand mechanisms of drug resistance in cancer therapies, helping to develop strategies to overcome this challenge.
  • Combination Therapies: It is being investigated for use in combination with other chemotherapeutic agents to improve treatment outcomes and reduce side effects in cancer patients.

Citations