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Catalog Number:
22152
CAS Number:
53-86-1
Indomethacin
Purity:
98 - 102% (Assay, on dried basis)
Synonym(s):
1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid
Hazmat
Documents
$30.00 /25G
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Product Information

Indomethacin is a potent nonsteroidal anti-inflammatory drug (NSAID) widely recognized for its effectiveness in alleviating pain and inflammation. This compound is particularly valuable in the treatment of various conditions, including arthritis, gout, and other inflammatory disorders. Its unique mechanism of action involves the inhibition of cyclooxygenase (COX) enzymes, which play a crucial role in the synthesis of prostaglandins, thereby reducing pain and swelling. Researchers and healthcare professionals appreciate Indomethacin for its rapid onset of action and its ability to provide significant relief in acute and chronic pain scenarios.

In addition to its therapeutic applications, Indomethacin has been utilized in various research settings, particularly in studies focused on inflammation and pain pathways. Its effectiveness in managing postoperative pain and its potential role in cancer pain management make it a compound of interest in both clinical and laboratory environments. With its established efficacy and ongoing research into its broader applications, Indomethacin remains a critical tool for healthcare providers and researchers alike.

Synonyms
1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid
CAS Number
53-86-1
Purity
98 - 102% (Assay, on dried basis)
Molecular Formula
C19H16ClNO4
Molecular Weight
357.79
MDL Number
MFCD00057095
PubChem ID
3715
Melting Point
158 - 162 ?C
Appearance
White or off-white crystalline powder
General Information
Synonyms
1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid
CAS Number
53-86-1
Purity
98 - 102% (Assay, on dried basis)
Molecular Formula
C19H16ClNO4
Molecular Weight
357.79
MDL Number
MFCD00057095
PubChem ID
3715
Melting Point
158 - 162 ?C
Appearance
White or off-white crystalline powder
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Indomethacin is widely utilized in research focused on:

  • Pain Management: Commonly prescribed for its anti-inflammatory properties, it effectively alleviates pain associated with conditions like arthritis and gout, making it a staple in pain relief therapies.
  • Cardiovascular Health: Research shows that Indomethacin can help reduce inflammation in cardiovascular diseases, potentially improving outcomes for patients with heart conditions.
  • Post-Surgical Recovery: Its anti-inflammatory effects are beneficial in managing pain and swelling after surgical procedures, aiding quicker recovery for patients.
  • Research in Oncology: Studies are exploring its potential role in cancer treatment, particularly in inhibiting tumor growth and metastasis, which could lead to innovative therapies.
  • Veterinary Medicine: Indomethacin is also used in veterinary practices to treat inflammation and pain in animals, showcasing its versatility across species.

Citations