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Catalog Number:
22123
CAS Number:
59865-13-3
Cyclosporin A
Grade:
USP
Purity:
97.0 - 101.5% (Assay, on dry basis)
Synonym(s):
Cyclosporin
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Product Information

Cyclosporin A is a potent immunosuppressant widely recognized for its critical role in organ transplantation and autoimmune disease management. This cyclic peptide, derived from the fungus Tolypocladium inflatum, is particularly effective in preventing organ rejection in transplant patients by inhibiting T-cell activation and proliferation. Its unique mechanism of action makes it invaluable in clinical settings, allowing for improved graft survival rates and enhanced patient outcomes. Beyond transplantation, Cyclosporin A is also utilized in treating conditions such as rheumatoid arthritis and psoriasis, showcasing its versatility in therapeutic applications.

In addition to its medical uses, Cyclosporin A has garnered attention in research for its potential in studying cellular signaling pathways and immune responses. Its ability to modulate immune function opens avenues for innovative treatments in various fields, including oncology and chronic inflammatory diseases. Researchers appreciate Cyclosporin A not only for its efficacy but also for its relatively favorable safety profile compared to other immunosuppressants, making it a preferred choice in many therapeutic regimens.

Synonyms
Cyclosporin
CAS Number
59865-13-3
Purity
97.0 - 101.5% (Assay, on dry basis)
Grade
USP
Molecular Formula
C62H111N11O12
Molecular Weight
1202.64
MDL Number
MFCD00274558
PubChem ID
2909
Appearance
White to almost white powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Cyclosporin
CAS Number
59865-13-3
Purity
97.0 - 101.5% (Assay, on dry basis)
Grade
USP
Molecular Formula
C62H111N11O12
Molecular Weight
1202.64
MDL Number
MFCD00274558
PubChem ID
2909
Appearance
White to almost white powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Cyclosporin A is widely utilized in research focused on:

  • Organ Transplantation: It is a critical immunosuppressant used to prevent organ rejection in transplant patients, helping to improve survival rates and quality of life.
  • Autoimmune Diseases: This compound is effective in treating conditions like rheumatoid arthritis and psoriasis by modulating the immune response, offering relief to patients.
  • Research in Immunology: Cyclosporin A serves as a valuable tool in studying immune system functions and mechanisms, aiding researchers in developing new therapies.
  • Dermatology: It is used in topical formulations for skin conditions, providing targeted treatment with fewer systemic side effects compared to oral medications.
  • Pharmaceutical Development: The compound is often used as a reference standard in drug formulation studies, ensuring the efficacy and safety of new medications.

Citations