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Catalog Number:
21809
CAS Number:
442-51-3
Harmine
Purity:
≥ 99% (GC)
Synonym(s):
7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole, 6-Methoxyharmane
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Product Information

Harmine is a naturally occurring alkaloid found in various plant species, particularly in the seeds of Peganum harmala and the bark of Banisteriopsis caapi. This compound is recognized for its psychoactive properties and has been extensively studied for its potential therapeutic applications. Harmine acts as a reversible inhibitor of monoamine oxidase A (MAO-A), making it a valuable compound in the field of psychopharmacology. Its unique ability to modulate neurotransmitter levels positions it as a candidate for research into treatments for mood disorders, anxiety, and even neurodegenerative diseases.

In addition to its medicinal potential, harmine has garnered interest in the realm of natural product synthesis and as a tool in neuroscience research. Its role in traditional medicine, particularly in shamanic practices, highlights its cultural significance and ongoing relevance in ethnopharmacology. Researchers and industry professionals can leverage harmine's properties for innovative applications in drug development and holistic health solutions, making it a compound of great interest in both academic and commercial settings.

Synonyms
7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole, 6-Methoxyharmane
CAS Number
442-51-3
Purity
≥ 99% (GC)
Molecular Formula
C13H12N2O
Molecular Weight
212.25
MDL Number
MFCD00004958
PubChem ID
5280953
Melting Point
262-270 ºC
Appearance
White to off-white crystalline powder
Conditions
Store at 0-8 °C
General Information
Synonyms
7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole, 6-Methoxyharmane
CAS Number
442-51-3
Purity
≥ 99% (GC)
Molecular Formula
C13H12N2O
Molecular Weight
212.25
MDL Number
MFCD00004958
PubChem ID
5280953
Melting Point
262-270 ºC
Appearance
White to off-white crystalline powder
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Harmine is widely utilized in research focused on:

  • Neuroscience: Harmine has shown potential in neuroprotective studies, aiding in the understanding of neurodegenerative diseases like Alzheimer's and Parkinson's. Researchers explore its ability to promote neuronal health and function.
  • Pharmacology: This compound is investigated for its psychoactive properties, particularly in the context of mental health treatments. Its role as a monoamine oxidase inhibitor (MAOI) makes it a candidate for developing therapies for depression and anxiety.
  • Traditional Medicine: Harmine is a key component in various herbal remedies, particularly in South American indigenous practices. Its applications in holistic healing and spiritual rituals are of interest to ethnobotanists and alternative medicine practitioners.
  • Cancer Research: Studies are exploring harmine's potential anti-cancer properties. It has been observed to inhibit the growth of certain cancer cell lines, making it a subject of interest for developing new cancer therapies.
  • Biotechnology: In the field of synthetic biology, harmine is being examined for its role in gene expression modulation. This application could lead to advancements in genetic engineering and biotechnology innovations.

Citations