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Catalog Number:
00679
CAS Number:
77-86-1
2-Amino-2-hydroxymethyl-1,3-propanediol
Purity:
99.8-100.1% (Assay, dried basis)
Synonym(s):
trisHydroxymethyl)aminomethane, TRIS buffer, Trometamol
Documents
$29.34 /250G
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Product Information

2-Amino-2-hydroxymethyl-1,3-propanediol, commonly known as Tris, is a versatile buffering agent widely used in biochemical and molecular biology applications. This compound is particularly valued for its ability to maintain stable pH levels in various laboratory settings, making it essential for experiments involving enzymes, proteins, and nucleic acids. Tris is often employed in the preparation of electrophoresis buffers, cell culture media, and during the purification processes of biomolecules. Its unique properties allow for effective stabilization of biological samples, ensuring reliable and reproducible results.

In addition to its buffering capabilities, Tris is recognized for its low toxicity and compatibility with a wide range of biological systems, making it a preferred choice among researchers. Its effectiveness in maintaining pH in the physiological range (around 7.0 to 9.0) enhances its utility in various applications, including DNA and RNA extraction, protein assays, and immunological studies. With its broad applicability and reliability, Tris remains a staple in laboratories focused on life sciences and biochemistry.

Synonyms
trisHydroxymethyl)aminomethane, TRIS buffer, Trometamol
CAS Number
77-86-1
Purity
99.8-100.1% (Assay, dried basis)
Molecular Formula
C4H11NO3
Molecular Weight
121.1
MDL Number
MFCD00004679
PubChem ID
6503
Appearance
White powder
Conditions
Store at RT
General Information
Synonyms
trisHydroxymethyl)aminomethane, TRIS buffer, Trometamol
CAS Number
77-86-1
Purity
99.8-100.1% (Assay, dried basis)
Molecular Formula
C4H11NO3
Molecular Weight
121.1
MDL Number
MFCD00004679
PubChem ID
6503
Appearance
White powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Amino-2-hydroxymethyl-1,3-propanediol is widely utilized in research focused on:

  • Pharmaceutical Formulations: This compound serves as a stabilizing agent in various drug formulations, enhancing the solubility and bioavailability of active ingredients, which is crucial for effective medication delivery.
  • Biotechnology Applications: It is commonly used in the production of buffers for biological assays, providing a stable pH environment that is essential for enzyme activity and cell culture processes.
  • Cosmetic Products: The compound acts as a moisturizing agent in skincare formulations, helping to improve skin hydration and texture, making it a popular choice in the cosmetic industry.
  • Food Industry: It is utilized as a food additive to enhance the stability and shelf-life of various products, ensuring quality and safety in food preservation.
  • Laboratory Research: Researchers leverage its properties in various chemical syntheses and analytical methods, facilitating experiments that require precise pH control and stability.

Citations