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Catalog Number:
00298
CAS Number:
77-86-1
Tris(hydroxymethyl)aminomethane
Grade:
ACS reagent
Purity:
99.8 - 100.1% (Assay by titration)
Synonym(s):
2-Amino-2-(hydroxymethyl)-1,3-propanediol, Tris base, Trometamol
Documents
$25.00 /100G
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Product Information

Tris(hydroxymethyl)aminomethane, commonly known as TRIS, is a versatile buffering agent widely utilized in biochemical and molecular biology applications. Its unique structure allows it to maintain a stable pH in various biological systems, making it an essential component in buffer solutions for electrophoresis, chromatography, and cell culture. Researchers appreciate TRIS for its low absorbance in the UV range, which is particularly beneficial in spectrophotometric assays, ensuring accurate measurements without interference.

In addition to its role in laboratory settings, TRIS is also employed in the formulation of pharmaceuticals and cosmetics, where it helps to stabilize active ingredients and enhance product efficacy. Its compatibility with a wide range of biological molecules further underscores its importance in research and development. With its ability to provide consistent pH control, TRIS is an invaluable tool for scientists aiming to optimize experimental conditions and achieve reliable results.

Synonyms
2-Amino-2-(hydroxymethyl)-1,3-propanediol, Tris base, Trometamol
CAS Number
77-86-1
Purity
99.8 - 100.1% (Assay by titration)
Grade
ACS reagent
Molecular Formula
C4H11NO3
Molecular Weight
121.1
MDL Number
MFCD00004679
PubChem ID
6503
Appearance
White powder or white crystalline powder
Conditions
Store at RT
General Information
Synonyms
2-Amino-2-(hydroxymethyl)-1,3-propanediol, Tris base, Trometamol
CAS Number
77-86-1
Purity
99.8 - 100.1% (Assay by titration)
Grade
ACS reagent
Molecular Formula
C4H11NO3
Molecular Weight
121.1
MDL Number
MFCD00004679
PubChem ID
6503
Appearance
White powder or white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Tris(hydroxymethyl)aminomethane is widely utilized in research focused on:

  • Biological Buffers: This compound is a key ingredient in buffer solutions, helping to maintain stable pH levels in biological experiments, which is crucial for enzyme activity and cell culture.
  • Pharmaceutical Formulations: It is often used in the development of drug formulations, providing a stable environment for active ingredients, enhancing their efficacy and shelf-life.
  • Analytical Chemistry: Researchers employ it in various analytical techniques, such as chromatography, to ensure consistent pH conditions, improving the accuracy of results.
  • Biotechnology Applications: In molecular biology, it serves as a stabilizer for proteins and nucleic acids, facilitating experiments like PCR and protein assays.
  • Cosmetic and Personal Care Products: The compound is also found in cosmetic formulations, where it acts as a pH adjuster, ensuring product stability and skin compatibility.

Citations