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Catalog Number:
38492
CAS Number:
1405-20-5
Polymyxin B sulfate salt powder
Grade:
suitable for cell culture
Documents
$78.42 /5MU
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Product Information

Polymyxin B sulfate salt powder is a potent antibiotic compound widely utilized in the medical and pharmaceutical industries for its effectiveness against Gram-negative bacterial infections. This compound is particularly valuable in the formulation of topical ointments and eye drops, where it serves as a critical agent in treating infections caused by bacteria such as Pseudomonas aeruginosa and Escherichia coli. Its unique mechanism of action disrupts bacterial cell membranes, making it an essential choice for healthcare professionals seeking reliable treatment options for resistant infections.

In addition to its therapeutic applications, Polymyxin B sulfate is also employed in laboratory settings for microbiological studies and as a selective agent in cell culture, allowing researchers to investigate bacterial resistance mechanisms and develop new antimicrobial strategies. Its stability and solubility in various solvents enhance its versatility, making it an indispensable tool in both clinical and research environments. With its proven efficacy and broad applicability, Polymyxin B sulfate salt powder remains a cornerstone in the fight against bacterial infections.

CAS Number
1405-20-5
Grade
suitable for cell culture
Molecular Formula
C55H96N16O13·2H2SO4
Molecular Weight
1385.0
MDL Number
MFCD00131991
PubChem ID
5702105
Appearance
White to almost white powder
Optical Rotation
[a]20D = -78 to -90 °
Conditions
Store at 0 - 8 °C
Potency
≥ 6000 IU/MG (dried basis)
General Information
CAS Number
1405-20-5
Grade
suitable for cell culture
Molecular Formula
C55H96N16O13·2H2SO4
Molecular Weight
1385.0
MDL Number
MFCD00131991
PubChem ID
5702105
Appearance
White to almost white powder
Optical Rotation
[a]20D = -78 to -90 °
Conditions
Store at 0 - 8 °C
Potency
≥ 6000 IU/MG (dried basis)
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Polymyxin B sulfate salt powder is widely utilized in research focused on:

  • Antibiotic Development: It serves as a critical component in developing new antibiotics, particularly against Gram-negative bacterial infections, addressing the growing concern of antibiotic resistance.
  • Topical Treatments: Commonly used in topical formulations to treat skin infections, it provides effective antibacterial action while minimizing systemic absorption, making it ideal for localized treatment.
  • Pharmaceutical Research: In drug formulation studies, it helps researchers understand the mechanisms of antibiotic action and resistance, facilitating the development of more effective therapies.
  • Laboratory Testing: Utilized in microbiology labs for susceptibility testing, it aids in determining the effectiveness of antibiotics against specific bacterial strains, crucial for guiding treatment decisions.
  • Veterinary Medicine: Employed in veterinary applications to treat infections in animals, it ensures the health and well-being of livestock and pets, highlighting its versatility beyond human medicine.

Citations