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Catalog Number:
38484
CAS Number:
859-18-7
Lincomycin hydrochloride
Grade:
suitable for cell culture
Synonym(s):
Methyl6,8-dideoxy-6-(1-methyl-4-propyl-2-pyrrolidinecarboxamido)-1-thio-D-erythro-a-D-galactooctopyranosidehydrochloride
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$46.07 /1G
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Product Information

Lincomycin hydrochloride is a potent antibiotic known for its effectiveness against a variety of Gram-positive bacteria and certain anaerobic infections. This compound is particularly valuable in clinical settings for treating serious infections caused by organisms resistant to penicillin. Its mechanism of action involves inhibiting bacterial protein synthesis, making it a crucial option for patients with allergies to penicillin or those who have infections caused by resistant strains. Lincomycin hydrochloride is commonly used in both human and veterinary medicine, showcasing its versatility in treating conditions such as osteomyelitis, pneumonia, and skin infections.

In addition to its therapeutic applications, Lincomycin hydrochloride is also utilized in research settings to study bacterial resistance mechanisms and antibiotic efficacy. Its unique structure allows for specific interactions with bacterial ribosomes, providing insights into the development of new antibiotics. With its established safety profile and effectiveness, Lincomycin hydrochloride remains a key player in the fight against bacterial infections, offering healthcare professionals a reliable tool in their therapeutic arsenal.

Synonyms
Methyl6,8-dideoxy-6-(1-methyl-4-propyl-2-pyrrolidinecarboxamido)-1-thio-D-erythro-a-D-galactooctopyranosidehydrochloride
CAS Number
859-18-7
Grade
suitable for cell culture
Molecular Formula
C18H34N2O6S·HCl
Molecular Weight
443.0
MDL Number
MFCD00083647
PubChem ID
21872023
Melting Point
156 - 158 °C
Appearance
White or almost white crystalline powder
Optical Rotation
[a]20D = 135 - 150 °
Conditions
Store at 0 - 8 °C
Potency
800 - 900 u/mg
General Information
Synonyms
Methyl6,8-dideoxy-6-(1-methyl-4-propyl-2-pyrrolidinecarboxamido)-1-thio-D-erythro-a-D-galactooctopyranosidehydrochloride
CAS Number
859-18-7
Grade
suitable for cell culture
Molecular Formula
C18H34N2O6S·HCl
Molecular Weight
443.0
MDL Number
MFCD00083647
PubChem ID
21872023
Melting Point
156 - 158 °C
Appearance
White or almost white crystalline powder
Optical Rotation
[a]20D = 135 - 150 °
Conditions
Store at 0 - 8 °C
Potency
800 - 900 u/mg
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Lincomycin hydrochloride is widely utilized in research focused on:

  • Antibiotic Treatment: It is primarily used to treat bacterial infections, especially those caused by anaerobic bacteria. This makes it essential in clinical settings, particularly for patients allergic to penicillin.
  • Veterinary Medicine: Lincomycin hydrochloride is effective in treating infections in livestock and pets, ensuring animal health and productivity in the agricultural sector.
  • Research on Antibiotic Resistance: Researchers use this compound to study mechanisms of antibiotic resistance, helping to develop new strategies for combating resistant bacterial strains.
  • Pharmaceutical Development: It serves as a model compound in the development of new antibiotics, providing insights into structure-activity relationships that can lead to more effective drugs.
  • Topical Formulations: Lincomycin hydrochloride is included in certain topical medications for skin infections, offering a targeted approach to treatment with minimal systemic effects.

Citations