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Catalog Number:
38391
CAS Number:
72558-82-8
Ceftazidime (contains ca. 10% Na2CO3)
Grade:
Meets USP Specification
Purity:
95 - 102% (Assay on dried basis)
Synonym(s):
CAZ (contains ca. 10% Na2CO3)
Documents
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Product Information

Ceftazidime is a broad-spectrum cephalosporin antibiotic renowned for its efficacy against a wide range of Gram-negative bacteria, making it a vital asset in clinical settings. This compound is particularly effective in treating severe infections, including those caused by Pseudomonas aeruginosa, and is commonly used in hospital environments for patients with compromised immune systems. Its unique structure, which includes a thiazole ring and a pyridine moiety, enhances its antibacterial activity and stability, allowing for effective treatment of infections that are resistant to other antibiotics.

In addition to its clinical applications, Ceftazidime is also utilized in research settings to study antibiotic resistance mechanisms and to develop new therapeutic strategies. Its formulation, which contains approximately 10% sodium carbonate, aids in maintaining the stability of the active ingredient, ensuring consistent performance in various applications. Researchers and healthcare professionals appreciate Ceftazidime for its reliability and effectiveness, making it a preferred choice in both treatment and research scenarios.

Synonyms
CAZ (contains ca. 10% Na2CO3)
CAS Number
72558-82-8
Purity
95 - 102% (Assay on dried basis)
Grade
Meets USP Specification
Molecular Formula
C22H22N6O7S2
Molecular Weight
546.57
MDL Number
MFCD00072034
PubChem ID
2650
Appearance
White to yellowish crystalline powder
Optical Rotation
[a]D20 = -22 to -26 ° (Lit.)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
CAZ (contains ca. 10% Na2CO3)
CAS Number
72558-82-8
Purity
95 - 102% (Assay on dried basis)
Grade
Meets USP Specification
Molecular Formula
C22H22N6O7S2
Molecular Weight
546.57
MDL Number
MFCD00072034
PubChem ID
2650
Appearance
White to yellowish crystalline powder
Optical Rotation
[a]D20 = -22 to -26 ° (Lit.)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Ceftazidime is widely utilized in research focused on:

  • Antibiotic Therapy: It is primarily used to treat infections caused by Gram-negative bacteria, making it essential in hospitals for patients with severe infections.
  • Clinical Research: Ceftazidime is often employed in clinical trials to evaluate its effectiveness against resistant bacterial strains, contributing to the development of new treatment protocols.
  • Pharmaceutical Development: The compound serves as a model for synthesizing new cephalosporins, helping researchers innovate and improve antibiotic properties.
  • Infection Control in Immunocompromised Patients: It is crucial in managing infections in patients undergoing chemotherapy or organ transplants, where the risk of infection is significantly heightened.
  • Veterinary Medicine: Ceftazidime is also used in treating bacterial infections in animals, ensuring the health and safety of livestock and pets.

Citations