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Catalog Number:
38381
CAS Number:
118081-37-1
Ceftibuten hydrate
Purity:
≥ 95% (HPLC)
Synonym(s):
(6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-4-carboxy-1-oxo-2-buten-1-yl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid hydrate
Documents
$267.20 /25MG
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Product Information

Ceftibuten hydrate is a broad-spectrum cephalosporin antibiotic that is particularly effective against a variety of gram-negative and some gram-positive bacteria. This compound is widely utilized in the treatment of respiratory tract infections, urinary tract infections, and skin infections, making it a valuable asset in both clinical and pharmaceutical settings. Its unique structure enhances its stability against beta-lactamases, which are enzymes produced by certain bacteria to resist antibiotic treatment, thereby increasing its efficacy in combating resistant strains.

Researchers and healthcare professionals appreciate Ceftibuten hydrate for its favorable pharmacokinetic properties, including good oral bioavailability and a long half-life, which allows for less frequent dosing compared to other antibiotics. This makes it an ideal choice for outpatient treatment regimens. Additionally, its formulation as a hydrate ensures optimal solubility and absorption, further enhancing its therapeutic potential. With its proven track record in clinical applications, Ceftibuten hydrate remains a critical component in the fight against bacterial infections.

Synonyms
(6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-4-carboxy-1-oxo-2-buten-1-yl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid hydrate
CAS Number
118081-37-1
Purity
≥ 95% (HPLC)
Molecular Formula
C15H14N4O6S2·xH2O
Molecular Weight
410.42
MDL Number
MFCD00864918
Appearance
White to light yellow to light orange powder to crystal
Optical Rotation
135 - 155 ° (C=1, pH 8 Phosphate buffer (calculated on anhydrous substance))
Conditions
Store at < 0 °C
General Information
Synonyms
(6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-4-carboxy-1-oxo-2-buten-1-yl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid hydrate
CAS Number
118081-37-1
Purity
≥ 95% (HPLC)
Molecular Formula
C15H14N4O6S2·xH2O
Molecular Weight
410.42
MDL Number
MFCD00864918
Appearance
White to light yellow to light orange powder to crystal
Optical Rotation
135 - 155 ° (C=1, pH 8 Phosphate buffer (calculated on anhydrous substance))
Conditions
Store at < 0 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Ceftibuten hydrate is widely utilized in research focused on:

  • Antibiotic Development: It serves as a crucial compound in developing new antibiotics, particularly for treating respiratory tract infections caused by resistant bacteria.
  • Pharmaceutical Formulations: This compound is used in formulating oral medications, providing effective treatment options for patients with bacterial infections.
  • Clinical Research: Ceftibuten hydrate is often studied in clinical trials to evaluate its efficacy and safety, helping to establish guidelines for its use in various patient populations.
  • Microbiology Studies: Researchers utilize it to assess bacterial susceptibility, aiding in understanding resistance patterns and informing treatment strategies.
  • Veterinary Medicine: It is also applied in veterinary practices for treating infections in animals, showcasing its versatility beyond human medicine.

Citations