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Catalog Number:
38376
CAS Number:
72559-06-9
Rifabutin
Grade:
meets USP specification
Purity:
950 - 1020 ìg/mg (Assay)
Synonym(s):
Ansamycin, LM-427
Documents
$35.00 /100MG
Pack Size Availability Price
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Product Information

Rifabutin is a potent antibiotic belonging to the ansamycin class, primarily used in the treatment of tuberculosis and other mycobacterial infections. Its unique mechanism of action involves inhibiting bacterial RNA synthesis, making it effective against resistant strains of Mycobacterium tuberculosis. This compound is particularly beneficial for patients with HIV co-infection, as it can be used as a prophylactic treatment to prevent the onset of disseminated Mycobacterium avium complex (MAC) disease.

In addition to its therapeutic applications, Rifabutin is also utilized in research settings to study antibiotic resistance and the efficacy of combination therapies. Its favorable pharmacokinetic properties, including a long half-life and good oral bioavailability, make it a preferred choice for clinicians aiming to optimize treatment regimens. Researchers and healthcare professionals appreciate Rifabutin for its ability to maintain effectiveness in challenging cases, providing a reliable option in the fight against resistant infections.

Synonyms
Ansamycin, LM-427
CAS Number
72559-06-9
Purity
950 - 1020 ìg/mg (Assay)
Grade
meets USP specification
Molecular Formula
C46H62N4O11
Molecular Weight
847.02
MDL Number
MFCD00866816
Appearance
Reddish-violet amorphous powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Ansamycin, LM-427
CAS Number
72559-06-9
Purity
950 - 1020 ìg/mg (Assay)
Grade
meets USP specification
Molecular Formula
C46H62N4O11
Molecular Weight
847.02
MDL Number
MFCD00866816
Appearance
Reddish-violet amorphous powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Rifabutin is widely utilized in research focused on

  • Treatment of Tuberculosis: Primarily used as an antibiotic to treat tuberculosis, especially in patients with HIV, enhancing patient outcomes and reducing the risk of drug resistance.
  • HIV Co-infection Management: Effective in managing opportunistic infections in HIV-positive patients, providing a critical option for healthcare providers in improving overall patient health.
  • Pharmaceutical Research: Employed in the development of new formulations and delivery methods, aiding researchers in creating more effective treatments with fewer side effects.
  • Clinical Trials: Frequently used in clinical studies to evaluate its efficacy and safety, contributing to the advancement of medical knowledge and treatment protocols.
  • Public Health Initiatives: Plays a role in global health programs aimed at controlling tuberculosis, particularly in high-burden countries, supporting efforts to reduce disease prevalence.

Citations