Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
38354
CAS Number:
137862-53-4
Valsartan
Purity:
≥ 98% (HPLC)
Synonym(s):
N-Valeryl-N-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-L-valine
Documents
$68.20 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Valsartan is an angiotensin II receptor antagonist primarily used in the treatment of hypertension and heart failure. This compound works by blocking the action of angiotensin II, a substance in the body that causes blood vessels to constrict, thereby promoting vasodilation and lowering blood pressure. Valsartan is recognized for its effectiveness in reducing the risk of cardiovascular events and is often prescribed for patients with left ventricular dysfunction following myocardial infarction. Its unique formulation allows for improved bioavailability and a favorable side effect profile compared to other antihypertensive agents, making it a preferred choice among healthcare professionals.

In addition to its primary use in managing high blood pressure, Valsartan has shown potential in treating chronic kidney disease and diabetic nephropathy, highlighting its versatility in various therapeutic areas. Researchers are also exploring its applications in combination therapies, which may enhance its efficacy and patient compliance. With its proven track record and ongoing research, Valsartan remains a vital compound in modern cardiovascular treatment strategies.

Synonyms
N-Valeryl-N-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-L-valine
CAS Number
137862-53-4
Purity
≥ 98% (HPLC)
Molecular Formula
C24H29N5O3
Molecular Weight
435.53
MDL Number
MFCD00865840
PubChem ID
5650
Melting Point
117 °C
Appearance
White to almost white powder to crystal
Optical Rotation
-63 to -67 ° (C=1, Methanol)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
N-Valeryl-N-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-L-valine
CAS Number
137862-53-4
Purity
≥ 98% (HPLC)
Molecular Formula
C24H29N5O3
Molecular Weight
435.53
MDL Number
MFCD00865840
PubChem ID
5650
Melting Point
117 °C
Appearance
White to almost white powder to crystal
Optical Rotation
-63 to -67 ° (C=1, Methanol)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Valsartan is widely utilized in research focused on

  • Hypertension Management: It is primarily used as an antihypertensive medication, helping to lower blood pressure in patients with hypertension, which can reduce the risk of heart attacks and strokes.
  • Heart Failure Treatment: Valsartan is effective in treating heart failure, improving the heart's ability to pump blood and enhancing the quality of life for patients.
  • Post-Myocardial Infarction Therapy: Following a heart attack, valsartan can be prescribed to prevent further cardiovascular events, aiding in recovery and long-term heart health.
  • Research in Cardiovascular Diseases: It is often studied in clinical trials to evaluate its effectiveness in various cardiovascular conditions, providing valuable data for future treatments.
  • Combination Therapy: Valsartan is frequently used in combination with other medications, such as diuretics, to enhance therapeutic effects and improve patient outcomes in managing complex cardiovascular issues.

Citations