Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
38336
CAS Number:
113942-30-6
Temozolomide acid
Purity:
≥ 98% (HPLC)
Synonym(s):
3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylicacid
Documents
$94.54 /50MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Temozolomide acid is a pivotal compound in the field of oncology, primarily recognized for its role as a metabolite of the chemotherapeutic agent temozolomide. This compound exhibits significant potential in the treatment of various types of brain tumors, particularly glioblastoma multiforme. Its unique structure allows it to cross the blood-brain barrier effectively, making it a valuable asset in targeted cancer therapies. Researchers and healthcare professionals appreciate its ability to induce apoptosis in cancer cells while minimizing damage to surrounding healthy tissues.

In addition to its therapeutic applications, temozolomide acid serves as a crucial intermediate in the synthesis of other pharmaceutical compounds, enhancing its relevance in drug development. Its stability and solubility characteristics make it suitable for formulation in various delivery systems, further expanding its utility in clinical settings. With ongoing research into its mechanisms of action and potential combinations with other agents, temozolomide acid remains a compound of interest for advancing cancer treatment strategies.

Synonyms
3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylicacid
CAS Number
113942-30-6
Purity
≥ 98% (HPLC)
Molecular Formula
C6H5N5O3
Molecular Weight
195.14
MDL Number
MFCD12032160
PubChem ID
11830328
Melting Point
162 - 164 °C (dec.)
Appearance
White to light yellow powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylicacid
CAS Number
113942-30-6
Purity
≥ 98% (HPLC)
Molecular Formula
C6H5N5O3
Molecular Weight
195.14
MDL Number
MFCD12032160
PubChem ID
11830328
Melting Point
162 - 164 °C (dec.)
Appearance
White to light yellow powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Temozolomide acid is widely utilized in research focused on

  • Cancer Treatment: This compound is primarily known for its role in treating glioblastoma multiforme, a type of brain cancer. It works by interfering with the DNA repair mechanism of cancer cells, making it a crucial option in oncology.
  • Pharmaceutical Development: Researchers use temozolomide acid in the development of new drugs aimed at enhancing the efficacy of existing cancer therapies. Its unique structure allows for modifications that can lead to more effective treatments.
  • Biochemical Research: In laboratories, it serves as a valuable tool for studying the mechanisms of drug resistance in cancer cells, helping scientists understand how tumors adapt to treatments.
  • Combination Therapies: This compound is often used in combination with other chemotherapeutic agents to improve overall treatment outcomes, showcasing its versatility in cancer therapy protocols.
  • Clinical Trials: Temozolomide acid is frequently involved in clinical trials aimed at exploring its effectiveness against various tumors, providing critical data that can lead to improved patient care.

Citations