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Catalog Number:
38300
CAS Number:
26921-17-5
Timolol maleate
Purity:
≥ 98% (HPLC)
Synonym(s):
S-(−)-1-(t-Butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanolmaleate, Timolol hydrogen maleate
Documents
$160.34 /200MG
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Product Information

Timolol maleate is a potent beta-blocker primarily utilized in the treatment of elevated intraocular pressure in conditions such as glaucoma and ocular hypertension. This compound is recognized for its ability to effectively reduce aqueous humor production, thereby lowering eye pressure and preventing potential vision loss. Its unique formulation as a maleate salt enhances its solubility and stability, making it an ideal choice for ophthalmic applications.

In addition to its ocular uses, Timolol maleate has shown promise in cardiovascular therapies, where it aids in managing hypertension and certain types of heart conditions. Its dual functionality makes it a valuable asset in both ophthalmic and cardiovascular pharmacology. Researchers and healthcare professionals appreciate its efficacy and versatility, as it provides a reliable option for patients requiring long-term management of their conditions. With its established safety profile and effectiveness, Timolol maleate continues to be a preferred choice in therapeutic settings.

Synonyms
S-(−)-1-(t-Butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanolmaleate, Timolol hydrogen maleate
CAS Number
26921-17-5
Purity
≥ 98% (HPLC)
Molecular Formula
C13H24N4O3S·C4H4O4
Molecular Weight
432.49
MDL Number
MFCD00058356
PubChem ID
329565
Melting Point
197 - 199 °C (dec.)
Appearance
White to almost white powder to crystal
Optical Rotation
-4.5 to -6.5 ° (C=1, 1 mol/L HCl)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
S-(−)-1-(t-Butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanolmaleate, Timolol hydrogen maleate
CAS Number
26921-17-5
Purity
≥ 98% (HPLC)
Molecular Formula
C13H24N4O3S·C4H4O4
Molecular Weight
432.49
MDL Number
MFCD00058356
PubChem ID
329565
Melting Point
197 - 199 °C (dec.)
Appearance
White to almost white powder to crystal
Optical Rotation
-4.5 to -6.5 ° (C=1, 1 mol/L HCl)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Timolol maleate is widely utilized in research focused on:

  • Ophthalmology: Primarily used as an eye drop solution to treat glaucoma and ocular hypertension by reducing intraocular pressure, making it essential for eye care professionals.
  • Cardiology: Employed in managing hypertension and heart conditions due to its ability to lower blood pressure and heart rate, providing a reliable option for cardiologists.
  • Pharmaceutical Research: Investigated for its potential in various formulations, allowing researchers to explore new therapeutic applications and improve existing medications.
  • Veterinary Medicine: Used in animal healthcare to manage similar conditions in pets, ensuring that veterinarians have effective treatment options available.
  • Clinical Trials: Frequently included in studies assessing the efficacy of beta-blockers, contributing to advancements in treatment protocols for cardiovascular diseases.

Citations