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Catalog Number:
38288
CAS Number:
13171-25-0
Trimetazidine dihydrochloride
Purity:
≥ 98% (HPLC)
Synonym(s):
1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride
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Product Information

Trimetazidine dihydrochloride is a well-regarded compound primarily utilized in the medical field for its cardioprotective properties. This medication is particularly effective in the treatment of angina pectoris, as it enhances myocardial metabolism and improves energy efficiency in heart cells. Its unique mechanism of action allows it to optimize glucose oxidation, thereby reducing the reliance on fatty acid metabolism, which is crucial during ischemic conditions. Researchers and healthcare professionals appreciate its role in improving exercise tolerance and overall cardiac function, making it a valuable addition to therapeutic regimens for patients with coronary artery disease.

In addition to its cardiovascular applications, trimetazidine dihydrochloride is being explored for its neuroprotective effects, potentially benefiting conditions such as Alzheimer's disease and other neurodegenerative disorders. Its favorable safety profile and minimal side effects further enhance its appeal in clinical settings. With ongoing research into its broader applications, trimetazidine dihydrochloride stands out as a versatile compound with significant potential for improving patient outcomes in various health conditions.

Synonyms
1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride
CAS Number
13171-25-0
Purity
≥ 98% (HPLC)
Molecular Formula
C14H22N2O3·2HCl
Molecular Weight
339.26
MDL Number
MFCD00243086
PubChem ID
83201
Melting Point
227 - 229 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride
CAS Number
13171-25-0
Purity
≥ 98% (HPLC)
Molecular Formula
C14H22N2O3·2HCl
Molecular Weight
339.26
MDL Number
MFCD00243086
PubChem ID
83201
Melting Point
227 - 229 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Trimetazidine dihydrochloride is widely utilized in research focused on

  • Cardiovascular Health: This compound is primarily used in the treatment of angina pectoris and other heart-related conditions, helping to improve blood flow and reduce chest pain.
  • Neuroprotective Applications: Research indicates its potential in protecting neurons from damage, making it a candidate for studies related to neurodegenerative diseases.
  • Metabolic Disorders: It has been explored for its role in enhancing glucose metabolism, which can be beneficial for patients with diabetes or metabolic syndrome.
  • Sports Medicine: Athletes may use it to improve endurance and performance by optimizing energy metabolism, although this application is subject to regulatory scrutiny.
  • Pharmaceutical Formulations: The compound is often included in various formulations due to its stability and efficacy, making it a valuable ingredient in cardiovascular drugs.

Citations