Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
38275
CAS Number:
133-67-5
Trichloromethiazide
Purity:
≥ 99% (Assay by titration)
Synonym(s):
6-Chloro-3-dichloromethyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide1,1-Dioxide
Documents
$221.63 /10G
Pack Size Availability Price
Request Bulk Quote
Product Information

Trichloromethiazide is a potent thiazide diuretic widely utilized in the treatment of hypertension and edema associated with various medical conditions, including heart failure and kidney disorders. This compound functions by inhibiting sodium reabsorption in the distal convoluted tubule of the nephron, promoting increased urine output and effectively lowering blood pressure. Its unique chemical structure allows for enhanced solubility and bioavailability, making it a preferred choice among healthcare professionals.

In addition to its primary applications in cardiovascular health, Trichloromethiazide is also explored in research settings for its potential role in managing conditions like diabetes insipidus and certain types of kidney stones. Its efficacy in promoting electrolyte balance while minimizing potassium loss distinguishes it from other diuretics, making it a valuable asset in therapeutic regimens. Researchers and clinicians appreciate its versatility and effectiveness, ensuring that Trichloromethiazide remains a staple in both clinical and laboratory environments.

Synonyms
6-Chloro-3-dichloromethyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide1,1-Dioxide
CAS Number
133-67-5
Purity
≥ 99% (Assay by titration)
Molecular Formula
C8H8Cl3N3O4S2
Molecular Weight
380.64
MDL Number
MFCD00057315
PubChem ID
5560
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
6-Chloro-3-dichloromethyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide1,1-Dioxide
CAS Number
133-67-5
Purity
≥ 99% (Assay by titration)
Molecular Formula
C8H8Cl3N3O4S2
Molecular Weight
380.64
MDL Number
MFCD00057315
PubChem ID
5560
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Trichloromethiazide is widely utilized in research focused on:

  • Hypertension Treatment: It is commonly used as a diuretic in the management of high blood pressure, helping to reduce fluid retention and lower blood pressure effectively.
  • Heart Failure Management: This compound is beneficial in treating heart failure by decreasing the workload on the heart through fluid elimination, improving patient outcomes.
  • Kidney Function Studies: In research settings, it aids in studying renal function and electrolyte balance, providing insights into kidney health and disease.
  • Pharmaceutical Formulations: It is incorporated into various drug formulations, enhancing their efficacy in treating cardiovascular conditions.
  • Veterinary Medicine: Trichloromethiazide is also used in veterinary practices for managing fluid retention in animals, showcasing its versatility across species.

Citations