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Catalog Number:
38274
CAS Number:
396-01-0
Triamterene
Purity:
≥ 98% (Assay by titration)
Synonym(s):
2,4,7-Triamino-6-phenylpteridine, 6-Phenyl-2,4,7-pteridinetriamine
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Product Information

Triamterene is a potent potassium-sparing diuretic widely utilized in the medical field for its ability to prevent potassium loss while promoting diuresis. This compound is particularly effective in treating conditions such as hypertension and edema associated with congestive heart failure, cirrhosis, and nephrotic syndrome. Its unique mechanism of action allows it to inhibit sodium reabsorption in the distal convoluted tubule of the nephron, making it a valuable option for patients requiring diuretic therapy without the risk of hypokalemia.

In addition to its therapeutic applications, Triamterene has garnered attention in research settings for its potential role in studying renal function and electrolyte balance. Its favorable safety profile and efficacy make it an essential compound for both clinical and research purposes. With its dual benefits of diuresis and potassium retention, Triamterene stands out among diuretics, providing a balanced approach to fluid management in various medical conditions.

Synonyms
2,4,7-Triamino-6-phenylpteridine, 6-Phenyl-2,4,7-pteridinetriamine
CAS Number
396-01-0
Purity
≥ 98% (Assay by titration)
Molecular Formula
C12H11N7
Molecular Weight
253.27
MDL Number
MFCD00006708
PubChem ID
5546
Appearance
Light yellow to yellow powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2,4,7-Triamino-6-phenylpteridine, 6-Phenyl-2,4,7-pteridinetriamine
CAS Number
396-01-0
Purity
≥ 98% (Assay by titration)
Molecular Formula
C12H11N7
Molecular Weight
253.27
MDL Number
MFCD00006708
PubChem ID
5546
Appearance
Light yellow to yellow powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Triamterene is widely utilized in research focused on

  • Diuretic Medication: Commonly prescribed for managing hypertension and edema, it helps the body eliminate excess fluid without causing potassium loss, making it a preferred choice in certain patient populations.
  • Pharmaceutical Research: Used in the development of new diuretics, researchers explore its mechanisms and potential combinations with other drugs to enhance efficacy and reduce side effects.
  • Animal Studies: In veterinary medicine, it is investigated for its effects on fluid retention and blood pressure in animals, providing insights that can translate to human medicine.
  • Analytical Chemistry: Employed in laboratory settings for the development of analytical methods to detect and quantify diuretics in biological samples, ensuring safety and compliance in pharmaceuticals.
  • Cardiovascular Studies: Researchers examine its impact on cardiovascular health, particularly its role in managing conditions associated with fluid overload, contributing to better treatment protocols.

Citations