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Catalog Number:
38243
CAS Number:
87333-19-5
Ramipril
Purity:
≥ 98% (HPLC)
Synonym(s):
(2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopenta[b]pyrrole-2-carboxylicacid
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Product Information

Ramipril is a potent angiotensin-converting enzyme (ACE) inhibitor widely utilized in the management of hypertension and heart failure. This compound is particularly effective in reducing blood pressure and improving cardiovascular outcomes, making it a staple in the treatment of various cardiovascular diseases. Its unique structure allows for enhanced bioavailability and a prolonged duration of action, which is beneficial for patients requiring consistent blood pressure control.

In addition to its primary use in hypertension management, Ramipril has shown promise in renal protection, particularly in patients with diabetes, by slowing the progression of diabetic nephropathy. Researchers and healthcare professionals appreciate its versatility, as it can be used in combination with other antihypertensive agents to achieve optimal therapeutic effects. The compound's safety profile and efficacy make it a preferred choice in clinical settings, ensuring better patient compliance and improved health outcomes.

Synonyms
(2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopenta[b]pyrrole-2-carboxylicacid
CAS Number
87333-19-5
Purity
≥ 98% (HPLC)
Molecular Formula
C23H32N2O5
Molecular Weight
416.52
MDL Number
MFCD00865775
PubChem ID
5038
Melting Point
107 - 111 °C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]D20 = 38 - 42 ° (C=1, 0.1N HCl in EtOH)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopenta[b]pyrrole-2-carboxylicacid
CAS Number
87333-19-5
Purity
≥ 98% (HPLC)
Molecular Formula
C23H32N2O5
Molecular Weight
416.52
MDL Number
MFCD00865775
PubChem ID
5038
Melting Point
107 - 111 °C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]D20 = 38 - 42 ° (C=1, 0.1N HCl in EtOH)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Ramipril is widely utilized in research focused on:

  • Hypertension Management: Commonly prescribed to lower high blood pressure, helping to reduce the risk of heart attacks and strokes. Its effectiveness in managing hypertension makes it a staple in cardiology.
  • Heart Failure Treatment: Used in patients with heart failure to improve symptoms and enhance quality of life. It aids in reducing the workload on the heart, making it a vital option for cardiologists.
  • Diabetic Nephropathy Prevention: Effective in protecting kidney function in diabetic patients, ramipril helps prevent the progression of kidney disease, which is crucial for endocrinologists and nephrologists.
  • Post-Myocardial Infarction Therapy: Administered after heart attacks to improve survival rates and reduce the risk of subsequent cardiovascular events, making it essential for post-operative care.
  • Research in Cardiovascular Pharmacology: Studied extensively for its mechanisms and effects on the cardiovascular system, providing valuable insights for researchers and pharmaceutical developers.

Citations