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Catalog Number:
38232
CAS Number:
135062-02-1
Repaglinide
Purity:
≥ 98% (Assay by titration, HPLC)
Synonym(s):
(S)-(+)-2-Ethoxy-4-[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]aminocarbonylmethyl]benzoicacid, Prandin
Documents
$172.36 /200MG
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Product Information

Repaglinide is a potent and rapid-acting oral hypoglycemic agent primarily used in the management of type 2 diabetes mellitus. As a member of the meglitinide class, it functions by stimulating insulin secretion from the pancreas, particularly after meals, thereby helping to control postprandial blood glucose levels. This unique mechanism makes Repaglinide particularly beneficial for patients who experience spikes in blood sugar after eating. Its quick onset of action allows for flexible dosing, making it an ideal choice for individuals who may have irregular eating patterns or prefer to tailor their medication to their meal schedule.

In addition to its primary use in diabetes management, Repaglinide has been explored in various research settings for its potential role in combination therapies, enhancing glycemic control when used alongside other antidiabetic medications. Its favorable pharmacokinetic profile, characterized by a short half-life, allows for easy adjustment of doses based on individual patient needs. This adaptability, combined with its efficacy, positions Repaglinide as a valuable option for healthcare professionals seeking to optimize diabetes treatment plans for their patients.

Synonyms
(S)-(+)-2-Ethoxy-4-[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]aminocarbonylmethyl]benzoicacid, Prandin
CAS Number
135062-02-1
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C27H36N2O4
Molecular Weight
452.6
MDL Number
MFCD00906179
PubChem ID
4547
Melting Point
131 - 135 °C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]D20 = 7 - 10 ° (C=1 in MeOH)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(S)-(+)-2-Ethoxy-4-[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]aminocarbonylmethyl]benzoicacid, Prandin
CAS Number
135062-02-1
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C27H36N2O4
Molecular Weight
452.6
MDL Number
MFCD00906179
PubChem ID
4547
Melting Point
131 - 135 °C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]D20 = 7 - 10 ° (C=1 in MeOH)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Repaglinide is widely utilized in research focused on:

  • Diabetes Management: Primarily used as an oral medication to control blood sugar levels in patients with type 2 diabetes, offering a rapid onset of action that helps manage post-meal glucose spikes effectively.
  • Pharmaceutical Development: Researchers explore its pharmacokinetics and pharmacodynamics to improve formulations and develop combination therapies, enhancing treatment options for diabetes.
  • Clinical Trials: Frequently involved in clinical studies assessing the efficacy and safety of new diabetes treatments, providing valuable data for regulatory approvals.
  • Comparative Effectiveness Research: Used in studies comparing the effectiveness of various diabetes medications, helping healthcare providers make informed treatment decisions.
  • Patient Adherence Studies: Investigated in research aimed at understanding patient adherence to diabetes therapies, as its dosing flexibility can improve compliance among patients.

Citations