Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
38221
CAS Number:
82640-04-8
Raloxifene hydrochloride
Grade:
USP
Purity:
97.5 - 102.0% (Assay on dried basis)
Synonym(s):
[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanonehydrochloride, Keoxifene hydrochloride
Documents
$22.43 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Raloxifene hydrochloride is a selective estrogen receptor modulator (SERM) that has gained prominence in the pharmaceutical industry, particularly for its applications in treating osteoporosis and reducing the risk of invasive breast cancer in postmenopausal women. This compound functions by mimicking estrogen's beneficial effects on bone density while simultaneously blocking its potential adverse effects on breast and uterine tissues. Its unique mechanism of action makes it a valuable alternative to traditional hormone replacement therapies, offering a targeted approach to managing osteoporosis and breast cancer risk.

In addition to its primary uses, Raloxifene hydrochloride has shown promise in cardiovascular health, potentially improving lipid profiles and reducing the risk of heart disease. Researchers and healthcare professionals appreciate its dual action, which not only supports bone health but also provides a protective effect against certain cancers. With its favorable safety profile and efficacy, Raloxifene hydrochloride is an essential compound for those looking to enhance women's health and well-being in clinical settings.

Synonyms
[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanonehydrochloride, Keoxifene hydrochloride
CAS Number
82640-04-8
Purity
97.5 - 102.0% (Assay on dried basis)
Grade
USP
Molecular Formula
C28H27NO4S·HCl
Molecular Weight
510.05
MDL Number
MFCD01938233
PubChem ID
54900
Melting Point
262 - 264 °C (Lit.)
Appearance
Light yellow to yellow to green powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanonehydrochloride, Keoxifene hydrochloride
CAS Number
82640-04-8
Purity
97.5 - 102.0% (Assay on dried basis)
Grade
USP
Molecular Formula
C28H27NO4S·HCl
Molecular Weight
510.05
MDL Number
MFCD01938233
PubChem ID
54900
Melting Point
262 - 264 °C (Lit.)
Appearance
Light yellow to yellow to green powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Raloxifene hydrochloride is widely utilized in research focused on:

  • Osteoporosis Treatment: Commonly prescribed to postmenopausal women, it helps reduce the risk of spinal fractures by mimicking estrogen's beneficial effects on bone density.
  • Breast Cancer Prevention: It is used as a preventive treatment for women at high risk of breast cancer, offering an alternative to traditional hormone replacement therapies.
  • Cardiovascular Health: Research indicates that it may improve lipid profiles, thereby potentially reducing the risk of heart disease in postmenopausal women.
  • Clinical Trials: Frequently involved in clinical studies assessing its efficacy and safety, providing valuable data for future therapeutic applications.
  • Research on Hormonal Therapies: Serves as a crucial compound in studies exploring selective estrogen receptor modulators (SERMs), contributing to advancements in hormone-related treatments.

Citations