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Catalog Number:
38219
CAS Number:
122320-73-4
Rosiglitazone
Purity:
≥ 99% (HPLC)
Synonym(s):
5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione
Documents
$59.79 /200MG
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Product Information

Rosiglitazone is a potent thiazolidinedione derivative primarily utilized in the management of type 2 diabetes. This compound functions as an agonist for the peroxisome proliferator-activated receptor gamma (PPAR-γ), playing a crucial role in enhancing insulin sensitivity and glucose metabolism. Its unique mechanism of action not only aids in lowering blood sugar levels but also contributes to favorable lipid profiles, making it a valuable option for patients with metabolic syndrome. Researchers and healthcare professionals appreciate Rosiglitazone for its ability to improve glycemic control while potentially reducing the risk of cardiovascular complications associated with diabetes.

In addition to its therapeutic applications, Rosiglitazone has garnered attention in pharmacological research for its anti-inflammatory properties and potential benefits in conditions such as polycystic ovary syndrome (PCOS) and non-alcoholic fatty liver disease (NAFLD). Its versatility in addressing multiple metabolic disorders highlights its significance in both clinical and research settings. With ongoing studies exploring its broader implications, Rosiglitazone remains a key compound for professionals seeking effective solutions in diabetes management and related health issues.

Synonyms
5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione
CAS Number
122320-73-4
Purity
≥ 99% (HPLC)
Molecular Formula
C18H19N3O3S
Molecular Weight
357.43
MDL Number
MFCD00871760
PubChem ID
77999
Melting Point
154 - 158 °C (Lit.)
Appearance
Off-white to white crystalline power
Conditions
Store at 2 - 8 °C
General Information
Synonyms
5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione
CAS Number
122320-73-4
Purity
≥ 99% (HPLC)
Molecular Formula
C18H19N3O3S
Molecular Weight
357.43
MDL Number
MFCD00871760
PubChem ID
77999
Melting Point
154 - 158 °C (Lit.)
Appearance
Off-white to white crystalline power
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Rosiglitazone is widely utilized in research focused on:

  • Diabetes Management: Primarily used in the treatment of type 2 diabetes, it helps improve insulin sensitivity, making it a vital option for patients struggling with blood sugar control.
  • Cardiovascular Research: Its effects on cardiovascular health are studied extensively, as it may influence heart function and vascular health, providing insights for developing therapies for diabetic patients at risk of heart disease.
  • Pharmacological Studies: Researchers explore its mechanisms of action and side effects, contributing to a better understanding of thiazolidinediones and their role in metabolic disorders.
  • Combination Therapies: Often investigated in combination with other antidiabetic medications, it can enhance treatment efficacy, offering a comprehensive approach to managing diabetes.
  • Regulatory Research: Its approval and market presence provide a case study for regulatory processes in drug development, helping professionals understand the complexities of bringing new medications to market.

Citations