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Catalog Number:
38215
CAS Number:
84225-95-6
Raclopride
Purity:
≥ 98% (Assay by titration, HPLC)
Synonym(s):
(S)-3,5-Dichloro-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-hydroxy-6-methoxybenzamide, (S)-Raclopride
Documents
$252.98 /200MG
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Product Information

Raclopride is a potent and selective dopamine D2 receptor antagonist, widely utilized in both research and clinical settings. This compound is particularly significant in the study of neuropsychiatric disorders, including schizophrenia and Parkinson's disease, where it aids in understanding dopamine's role in these conditions. Raclopride's unique properties allow it to be employed in PET imaging studies, providing valuable insights into dopamine receptor availability and function in the human brain. Its ability to selectively bind to D2 receptors makes it an essential tool for researchers investigating the pharmacological effects of antipsychotic medications and the underlying mechanisms of dopaminergic signaling.

In addition to its applications in neuroscience research, Raclopride has shown potential in the development of therapeutic strategies aimed at modulating dopamine activity. Its efficacy in animal models has opened avenues for exploring new treatments for addiction and mood disorders. With its well-characterized pharmacological profile, Raclopride stands out as a critical compound for advancing our understanding of dopamine-related pathologies and developing innovative therapeutic interventions.

Synonyms
(S)-3,5-Dichloro-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-hydroxy-6-methoxybenzamide, (S)-Raclopride
CAS Number
84225-95-6
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C15H20Cl2N2O3
Molecular Weight
347.24
MDL Number
MFCD02179386
PubChem ID
5118
Melting Point
52 - 56 °C
Appearance
White to light red to green powder to crystal
Optical Rotation
[a]D20 = -67 to -71 ° (C=2,Acetone)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(S)-3,5-Dichloro-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-hydroxy-6-methoxybenzamide, (S)-Raclopride
CAS Number
84225-95-6
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C15H20Cl2N2O3
Molecular Weight
347.24
MDL Number
MFCD02179386
PubChem ID
5118
Melting Point
52 - 56 °C
Appearance
White to light red to green powder to crystal
Optical Rotation
[a]D20 = -67 to -71 ° (C=2,Acetone)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Raclopride is widely utilized in research focused on:

  • Neuroscience Research: It serves as a radioligand in PET imaging studies to explore dopamine receptor activity, aiding in the understanding of various neurological disorders.
  • Pharmaceutical Development: Used in drug discovery processes to evaluate the efficacy of new antipsychotic medications, particularly those targeting dopamine receptors.
  • Behavioral Studies: Employed in animal models to assess the effects of dopamine antagonism on behavior, providing insights into addiction and mood disorders.
  • Clinical Trials: Involved in trials for schizophrenia treatments, helping researchers determine the safety and effectiveness of new therapeutic agents.
  • Biochemical Research: Utilized in studies investigating the biochemical pathways of neurotransmitter systems, contributing to a deeper understanding of mental health conditions.

Citations